Application of neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy in curative surgery for esophageal cancer: A meta-analysis

Table 1 Basic introduction of literature included in randomized controlled trials

Ref.	Case	TNM
Burmeister et al[8], 2011	75	Stage I-III
Stahl et al[9], 2017	119	Stage II-III
von Döbeln et al[10], 2019	181	Stage II-IV

Table 2 Basic data of literature included in case-control studies and cohort studies

Ref.	Case	TNM
Anderegg et al[11], 2017	313	Stage I-III
Esophageal Cancer Study Group Participating Centers[12], 2019	268	Stage I-III
Gawad et al[13], 2015	370	Stage II-IV
Markar et al[14], 2017	608	Stage II-III
Tian et al[15], 2020	827	Stage I-IV
Nakashima[16], 2018	120	Stage II-IV
Park et al[17], 2020	38	Stage II-III
Pucher et al[18], 2020	284	Stage I-III
Samson et al[19], 2016	7388	Stage I-III
Spicer et al[20], 2016	214	Stage IIIA
Stiles et al[21], 2019	338	Stage I-IV
Swisher et al[22], 2010	157	Stage I-III
Tang et al[23], 2023	264	Stage II-IV
Tercioti et al[24], 2011	97	Stage I-III
Tiesi et al[25], 2017	297	Stage II-IV
Jiang et al[26], 2022	299	Stage II-III
Zhou et al[27], 2020	423	NA

NA: Not available.

Table 3 Quality of case-control studies and cohort studies

Ref.	Research type	Study endpoint	NOS scoring
Anderegg et al[11], 2017	CCS	1-9	7
Esophageal Cancer Study Group Participating Centers[12], 2019	CCS	3, 4, and 6	7
Gawad et al[13], 2015	CCS	4	6
Markar et al[14], 2017	CCS	3, 5, 7, 8, and 9	7
Tian et al[15], 2020	CCS	3, 4, 5, and 7	7
Nakashima[16], 2018	CCS	3-8	7
Park et al[17], 2020	CCS	5, 7, 8, 9	6
Pucher et al[18], 2020	CCS	1-7 and 9	6
Samson et al[19], 2016	CCS	5, 6, and 7	6
Spicer et al[20], 2016	CCS	1-5, 7, 8, and 9	7
Stiles et al[21], 2019	CCS	1-4, 6-9	7
Swisher et al[22], 2010	CCS	3, 4, and 6-9	7
Tang et al[23], 2023	CCS	5	6
Tercioti et al[24], 2011	CCS	6, 7, and 9	6
Tiesi et al[25], 2017	CCS	3-8	7
Jiang et al[26], 2022	CCS	4	7
Zhou et al[27], 2020	CS	3 and 4	7

CCS: Case-control study; CS: Cohort Study; NOS: Newcastle Ottawa Scale.