Nomogram model predicting the overall survival for patients with primary gastric mucosa-associated lymphoid tissue lymphoma

Table 1 Clinical pathology characteristics of patients with primary gastric mucosa-associated lymphoid tissue in all subjects, the training and validation sets, n (%)

Variable	All cohort	Training cohort	Validation cohort	P valuea
Total	2604	1823	781
Age				0.423
<45	234(8.98)	168 (71.79)	66(28.21)
45-65	1040(39.94)	739 (71.06)	301(28.94)
≥65	1330(51.08)	916 (68.87)	414(31.13)
Sex				0.262
Male	1250(48.00)	862 (68.96)	388(31.04)
Female	1354(52.00)	961 (70.97)	393(29.03)
Race				0.699
White	2059(79.07)	1434 (69.65)	625(30.35)
Black	284(10.91)	201 (70.77)	83 (29.23)
Other	261(10.02)	188 (72.03)	73 (27.97)
Location				0.734
Upper third	314(12.06)	212 (67.52)	102(32.48)
Middle third	642(24.65)	455 (70.87)	187(29.13)
Low third	425(16.32)	291 (68.47)	134(31.53)
Stomach, NOS	1020(39.17)	723 (70.88)	297(29.12)
Overlapping lesion	203(7.80)	142 (69.95)	61 (30.05)
of stomach				0.516
Stage (Ann Arbor)		1452 (69.54)	636(30.46)
I	2088(80.18)	187 (73.91)	66 (26.09)
II	253(9.71)	47 (72.31)	18 (27.69)
III	65(2.50)	137 (69.19)	61 (30.81)
IV	198(7.60)			0.332
Surgery		1700 (70.25)	720(29.75)
No/unknown	2420(92.93)	123 (66.85)	61 (33.15)
Yes	184(7.07)			0.82
Chemotherapy		1440 (69.90)	620(30.10)
No/unknown	2060(79.11)	383 (70.40)	161(29.60)
Yes	544(20.89)			0.36
Radiation		1231 (70.58)	513(29.42)
No/unknown	1744(66.97)	592 (68.84)	268(31.16)
Yes	860(33.03)

^aχ² test.

Categorical variables were represented by n(%).The P value result is the comparison result between the training and validation groups.

Table 2 Multivariate analysis of overall survival for patients with primary gastric mucosa-associated lymphoid based on least absolute shrinkage and selection operator regression in the training set (n = 1823)

Variable		Multivariate		Analysis
		HR	95%CI of HR	P value
Age
< 45	Reference
45-65		4.290	1.881-9.815	0.001b
≥ 65		19.843	8.843-44.528	< 0.001c
Sex
Male
Female		0.722	0.606-0.860	< 0.001c
Race
White	Reference
Black		1.374	1.020-1.779	0.036a
Other		0.704	0.493-1.003	0.052
Stage (Ann Arbor)
I	Reference	1.437	1.084-1.904	0.012a
II		1.732	1.076-2.786	0.024a
III		1.844	1.401-2.428	< 0.001c
IV
Radiation	Reference
No/unknown
Yes		0.670	0.542-0.829

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.

OS: Overall survival; HR: Hazard ratio; CI: Confidence interval.