Mining The Cancer Genome Atlas database for tumor mutation burden and its clinical implications in gastric cancer

Table 1 Performance of the miRNA-based signature to predict tumor mutation burden in gastric cancer

Type	Training set	Testing set	Whole set
sensitivity	0.828	0.750	0.802
specificity	0.990	0.937	0.968
PPV	0.960	0.700	0.863
NPV	0.951	0.950	0.951
Accuracy	0.953	0.906	0.934
AUC	0.982	0.887	0.947

PPV: Positive predictive value; NPV: Negative predictive value; AUC: Area under curve.