Correlation between invasive microbiota in margin-surrounding mucosa and anastomotic healing in patients with colorectal cancer

Table 1 Clinicopathological characteristics

Characteristic	Overall	Anastomotic healing		P-value1
	(n = 37)	Well (n = 30)	Impaired (n = 7)
Age (mean ± SD), yr	67.97 ± 12.27	65.10 ± 11.36	80.29 ± 7.86	0.02
Body mass index (mean ± SD), kg/m2	21.50 ± 2.73	21.70 ± 2.70	20.64 ± 2.71	N.S.
Sex: Male/female	19/18	16/14	3/4	N.S.
Tumor location: Right colon/left colon/rectum	9/12/16	5/11/14	4/1/2	N.S.
Tumor size (mean ± SD), mm	47.97 ± 22.87	47.17 ± 20.75	51.43 ± 30.08	N.S.
T stage: t1/t2/t3/t4	2/9/2/24	1/7/2/20	1/2/0/4	N.S.
N stage: n0/n1/n2	25/10/2	21/7/2	4/3/0	N.S.
M stage: m0/m1	37/0	30/0	7/0	N.S.
TNM stage: I/II/III	9/16/12	6/15/9	3/1/3	N.S.
Differentiation: Poor/moderate-poor/moderate /well	0/15/21/1	0/12/18/0	0/3/3/1	N.S.
Morphology: Elevated/ulcerative/invasive	17/19/1	14/15/1	3/4/0	N.S.
Intestinal obstruction: Present/absent	5/32	3/27	2/5	N.S.
Transfusion, n	1	0	1	N.S.
Blood loss (mean ± SD), mL	66.81 ± 31.60	67.76 ± 30.78	62.86 ± 34.52	N.S.
Operative time (mean ± SD), h	2.82 ± 0.68	2.71 ± 0.70	2.84 ± 0.67	N.S.
C-reactive protein (mean ± SD), mg/L	93.23 ± 48.75	101.88 ± 45.54	64.81 ± 48.18	N.S.
Hemoglobin (mean ± SD), g/L	105.36 ± 25.46	108.41 ± 25.05	92.29 ± 22.93	N.S.
Albumin (mean ± SD), g/L	34.30 ± 12.72	35.11 ± 13.88	30.80 ± 3.72	N.S.

¹Wilcoxon test, chi-squared test, and paired t-test, as appropriate. N.S.: Not significant.