Retraction Note Open Access
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2865-2866
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2865
Retraction note to: RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer
Xue-Jun Wang, Yong Liu, Bin Ke, Li Zhang, Han Liang, Department of Gastric Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin 300060, China
ORCID number: Xue-Jun Wang (0000-0001-7215-5149); Han Liang (0000-0002-5674-0994).
Author contributions: Wang XJ designed and wrote the manuscript; Liu Y, Ke B, Zhang L, and Liang H analyzed the data; and all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors report no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Jun Wang, MD, Associate Professor, Department of Gastric Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Huanhu Xi Road, Tiyuan Bei, Hexi District, Tianjin 300060, China. wangxuejun20202020@163.com
Received: January 26, 2024
Revised: April 11, 2024
Accepted: April 19, 2024
Published online: June 15, 2024
Processing time: 140 Days and 20 Hours

Abstract

The authors have decided to retract the article published on World J Gastrointest Oncol (2023) for further consideration due to data errors and some misunderstandings in communication.

Key Words: Retraction note

Core Tip: We have decided to retract the article published on World J Gastrointest Oncol 2023 September 15; 15(9): 1531-1543 for further consideration due to data errors and some misunderstandings in communication.



TO THE EDITOR

Retraction Note to the article: RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. World J Gastrointest Oncol 2023; 15(9): 1531-1543 [PMID: 37746647 PMCID: PMC10514719 DOI: 10.4251/wjgo.v15.i9.1531]. The online version of the original article can be found at https://www.wjgnet.com/1948-5204/full/v15/i9/1531.htm.

We have reappraised our experiment, and will carry out subsequent research on this topic. We regret that there were data labeling errors in Figure 5I. The curves which represent si-CPSF6 and si-CPSF6+OV-IBSP groups were reversed. More importantly, we misdefined pyroptosis, therefore, we used flow cytometry (FITC Annexin V Apoptosis Detection Kit) to detect pyroptosis, and concluded that CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. After reviewing related literature, we found that the data from our study could not directly reflect the actual pyroptosis[1-3]. Consequently, our conclusion is not convincing. With the approval of all the authors and to avoid misleading the readers, we respectfully request to retract the article “RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. World J Gastrointest Oncol 2023; 15(9): 1531-1543 [PMID: 37746647 PMCID: PMC10514719 DOI: 10.4251/wjgo.v15.i9.1531].

We apologize to the readers and editors of the World J Gastrointest Oncol for these errors and for any inconvenience caused.

Footnotes

Provenance and peer review: Unsolicited article; Externally peer reviewed.

Peer-review model: Single blind

Specialty type: Oncology

Country of origin: China

Peer-review report’s classification

Scientific Quality: Grade C

Novelty: Grade D

Creativity or Innovation: Grade D

Scientific Significance: Grade D

P-Reviewer: Fabbri N, Italy S-Editor: Qu XL L-Editor: A P-Editor: Zhao S

References
1.  Yang Y, Chen HL, Wu SF, Bao W. CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma. Biochim Biophys Acta Gen Subj. 2024;1868:130497.  [PubMed]  [DOI]  [Cited in This Article: ]  [Reference Citation Analysis (0)]
2.  Telford WG. Multiparametric Analysis of Apoptosis by Flow Cytometry. Methods Mol Biol. 2024;2779:217-257.  [PubMed]  [DOI]  [Cited in This Article: ]  [Reference Citation Analysis (0)]
3.  Costigan A, Hollville E, Martin SJ. Discriminating Between Apoptosis, Necrosis, Necroptosis, and Ferroptosis by Microscopy and Flow Cytometry. Curr Protoc. 2023;3:e951.  [PubMed]  [DOI]  [Cited in This Article: ]  [Reference Citation Analysis (0)]