Analysis of the potential biological value of pyruvate dehydrogenase E1 subunit β in human cancer

Figure 13  Results of pyruvate dehydrogenase E1 subunit β expression validation. A: Pyruvate dehydrogenase E1 subunit β (PDHB) expression in the human normal hepatocyte cell line (L-O2) and human hepatoma cell lines (SMMC-7721, HepG2, Huh7, H-97); B: PDHB expression in the human normal gastric mucosal cell line (GES-1) and human gastric cancer cell lines (HGC-27, MGC-803, MKN-45); C: PDHB expression in the human normal colonic epithelial cell line (NCM460) and human colon cancer cell lines (SW620, HCT116); D: PDHB expression in the human normal breast cell line (MCF-10A) and breast cancer cell lines (MDA-MB-231, MCF-7); E: PDHB expression in the human normal prostate cell line (RWPE-2) and prostate cancer cell lines (PC-3, 22Rv1 and DU145); F: Validation of PDHB protein expression in the L-O2 and hepatoma cell lines (HepG2, SMMC-7721, Huh7, H-97); G: Quantitative plots; H: Validation of PDHB protein expression in the GES-1 and gastric cancer cell lines (MKN-45, AGS, HGC-27, MGC-803); I: Quantitative plots. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. PDHB: Pyruvate dehydrogenase E1 subunit β; L-O2: Human normal hepatocyte cell line; GES-1: Gastric mucosal cells; NS: Not significant.