Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?

doi:10.4251/wjgo.v8.i2.173

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Feb 15, 2016 (publication date) through Dec 24, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2016; 8(2): 173-185
Published online Feb 15, 2016. doi: 10.4251/wjgo.v8.i2.173

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Figure 1 Novel compounds under investigation and their predominant targets. EGFR: Epidermal growth factor receptor; VEGFR: Vascular endothelial growth factor receptor; PDGFR: Platelet derived growth factor receptor; FGFR: Fibroblast growth factor receptor; PI3K: Phosphatidylinositol-4,5-bisphosphate 3-kinase; mTOR: Mammalian target of rapamycin.

Citation: Thillai K, Ross P, Sarker D. Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis? World J Gastrointest Oncol 2016; 8(2): 173-185
URL: https://www.wjgnet.com/1948-5204/full/v8/i2/173.htm
DOI: https://dx.doi.org/10.4251/wjgo.v8.i2.173