Goblet cell carcinoid tumors of the appendix: An overview

Figure 1 Haematoxylin and eosin (H&E) stained sections showing the morphologic spectrum of goblet cell carcinoids (GCCs). A: The typical cells that are encountered in GCCs: clusters or aggregates of cells with abundant mucin-filled cytoplasm that compresses the nucleus and resembles a goblet cell (× 100); B: In areas the tumor cells can be less conspicuous and they are separated by large amounts of fibrous stroma (× 200); C: In some cases, several of the tumor cells are found within pools of extravasated mucin (× 200); D: Extension of the tumor into periappendiceal or mesoappendiceal fat is a common finding (× 200).

Figure 2 Tumor cells exhibit strong immunoreactivity for CK20 (× 200, anti-CK20).