Primary squamous cell carcinoma of the descending colon with pancreatic metastasis: A case report

Figure 1 Imaging findings. A: Computed tomography image showing circumferential wall thickening of the descending colon with luminal narrowing (yellow circle); B: Colonoscopic image of a circumferential ulcerative mass in the descending colon; C: Positron emission tomography-computed tomography image demonstrating hypermetabolic activity in the descending colon.

Figure 2 Pathology findings. A: Colon (20 × hematoxylin and eosin staining): Atypical cells arranged in nests and sheets with focal keratinization (indicated by yellow circles); B: Pancreas (20 × hematoxylin and eosin staining): Atypical cells arranged in nests and sheets with focal keratinization (indicated by yellow circles); C: 100 × Immunohistochemistry (IHC): Ki67 (+); D: 100 × IHC: P40 (+); E: 100 × IHC: Cytokeratin (CK) 5/6 (+); F: 100 × IHC: P63 (+); G: 100 × IHC: CK20 (-); H: 100 × IHC: Caudal-type homeobox protein 2 (-); I: 100 × IHC: Villin (-); J: 100 × IHC: CK7 (+); K: 100 × IHC: Pan-CK (+); L: 100 × IHC: Somatostatin receptor 2 (-).

Figure 3 Evolution of blood biomarkers. A: C-reactive protein; B: Procalcitonin; C: Cardiac troponin I; D: B-type natriuretic peptide. CRP: C-reactive protein; PCT: Procalcitonin; cTnI: Cardiac troponin I; BNP: B-type natriuretic peptide.