Correlation of tumor-associated macrophage density and proportion of M2 subtypes with the pathological stage of colorectal cancer

Figure 1 Complex array of cellular receptors of tumor-associated macrophages engaged in tumor-associated macrophage modulation. Created with BioRender.com.

Figure 2 Colorectal carcinoma. The invasive front (hematoxylin and eosin, × 40 magnification).

Figure 3 Macrophages at the tumor invasive front. A: CD 163+; B: CD 68+. Immunohistochemistry; × 40 magnification.

Figure 4 Tumor stroma infiltrated by macrophages, exhibiting membranous and cytoplasmic staining. A: CD 163+; B: CD 68+. Immunohistochemistry; × 200 magnification.

Figure 5 Univariate analysis of M2 proportion in the tumor stroma and front. A: Tumor stroma; B: Tumor front.