Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis

Figure 1 Levels of dynamic contrast-enhanced magnetic resonance imaging parameters and tumor markers in different T stages. A: Comparison of volume transfer constant between low and high stage groups; B: Comparison of rate constant between low and high stage groups; C: Comparison of extravascular extracellular volume fraction between low and high stage groups; D: Comparison of carbohydrate antigen 19-9 (CA19-9) between low and high stage groups; E: Comparison of CA125 between low and high stage groups. Ktrans: Volume transfer constant; Kep: Rate constant; Ve: Extravascular extracellular volume fraction; CA19-9: Carbohydrate antigen 199; CA12-5: Carbohydrate antigen 125.

Figure 2 Levels of dynamic contrast-enhanced magnetic resonance imaging parameters and tumor markers in different differentiation degrees. A: Comparison of volume transfer constant between low (L) and moderate + high (M + H) groups; B: Comparison of rate constant between L and M + H groups; C: Comparison of extravascular extracellular volume fraction between L and M + H groups; D: Comparison of carbohydrate antigen 19-9 (CA19-9) between L and M + H groups; E: Comparison of CA125 between L and M + H groups. M + H: Moderate + high; L: Low; Ktrans: Volume transfer constant; Kep: Rate constant; Ve: Extravascular extracellular volume fraction; CA19-9: Carbohydrate antigen 199; CA12-5: Carbohydrate antigen 125.

Figure 3 The areas under the curve of dynamic contrast-enhanced magnetic resonance imaging parameters for the diagnosis of T stage and differentiation degree. A: The areas under the curve (AUC) of volume transfer constant (Ktran) in the diagnosis of high and low stages; B: The AUC of extravascular extracellular volume fraction (Ve) in the diagnosis of high and low stages; C: The AUC of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters in the diagnosis of high and low stages; D: The AUC of Ktran in the diagnosis of moderate-high and low differentiation; E: The AUC of Ve in the diagnosis of moderate-high and low differentiation; F: The AUC of DCE-MRI parameters in the diagnosis of moderate-high and low differentiation. Ktrans: Volume transfer constant; Kep: Rate constant; Ve: Extravascular extracellular volume fraction; DCE-MRI: Dynamic contrast-enhanced magnetic resonance imaging.

Figure 4 The areas under the curve of dynamic contrast-enhanced magnetic resonance imaging parameters, carbohydrate antigen 19-9 and carbohydrate antigen 125 for the diagnosis of T stage and differentiation degree. A: The areas under the curve (AUC) of carbohydrate antigen 19-9 (CA19-9) in the diagnosis of high and low stages; B: The AUC of CA125 in the diagnosis of high and low stages; C: The AUC of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters plus tumor markers in the diagnosis of high and low stages; D: The AUC of CA19-9 in the diagnosis of moderate-high and low differentiation; E: The AUC of CA19-9 in the diagnosis of moderate-high and low differentiation; F: The AUC of DCE-MRI parameters plus tumor markers in the diagnosis of moderate-high and low differentiation. CA19-9: Carbohydrate antigen 199; CA125: Carbohydrate antigen 125; DCE-MRI: Dynamic contrast-enhanced magnetic resonance imaging.