Predictive model for non-malignant portal vein thrombosis associated with cirrhosis based on inflammatory biomarkers

Figure 1 The flowchart of present study. LASSO: Least absolute shrinkage and selection operator; PVT: Portal vein thrombosis; ROC: Receiver operating characteristic curve; DCA: Decision curve analysis.

Figure 2 Predictor selection for least absolute shrinkage and selection operator regression analysis. A: Least absolute shrinkage and selection operator coefficient profiles of the 21 variables; B: The mean−squared error was plotted vs log lambda. The left vertical dotted line shows the optimal values with the fewest criteria, whereas the right vertical dotted line reflects the single standard error criterion.

Figure 3 The predictive nomogram for portal vein thrombosis in patients with cirrhosis. PVV: Portal vein velocity; PLR: Platelet-to-lymphocyte ratio; ANRI: Aspartate transaminase to neutrophil ratio index; PLT: Platelet count; PVD: Portal vein diameter; D-D: D-dimer; GOV: Gastroesophageal varices.

Figure 4 The receiver operating characteristic curve (A), calibration curve (B), and decision curve analysis (C) for the training group. PVT: Portal vein thrombosis.

Figure 5 The receiver operating characteristic curve (A), calibration curve (B), and decision curve analysis (C) for the testing group. PVT: Portal vein thrombosis.

Figure 6 Comparison of area under the receiver operating characteristic between the nomogram and all independent risk factors in the training group (A) and testing group (B). PVV: Portal vein velocity; PLR: Platelet-to-lymphocyte ratio; ANRI: Aspartate transaminase to neutrophil ratio index; PLT: Platelet count; PVD: Portal vein diameter; D-D: D-dimer; GOV: Gastroesophageal varices.

Figure 7 Correlation matrix plot for independent risk factors. PVV: Portal vein velocity; PLR: Platelet-to-lymphocyte ratio; ANRI: Aspartate transaminase to neutrophil ratio index; PLT: Platelet count; PVD: Portal vein diameter; D-D: D-dimer; GOV: Gastroesophageal varices.

Figure 8 The interface for network calculator. PVV: Portal vein velocity; PLR: Platelet-to-lymphocyte ratio; ANRI: Aspartate transaminase to neutrophil ratio index; PLT: Platelet count; PVD: Portal vein diameter; D-D: D-dimer; GOV: Gastroesophageal varices.