Tumour response following preoperative chemotherapy is affected by body mass index in patients with colorectal liver metastases

Figure 1 Tumour regression grade for colorectal liver metastases after preoperative chemotherapy. A: Tumour regression grade 1 (TRG1), no residual cancer cells; B and C: TRG2, rare scattered residual cancer cells within fibrosis; D: TRG3, more residual tumour cells but fibrosis remains predominant; E: TRG4, residual tumour cells predominant; F: TRG5, absence of regressive changes.

Figure 2 Factors related to complete tumour response (multivariate regression analysis). BMI: Body mass index; CEA: Carcinoembryonic antigen; TRG: Tumour regression grade.

Figure 3 Kaplan-Meier survival curve: Impact of body mass index and tumour regression grade on progression-free survival. A: A better progression-free survival (PFS) was observed in patients with low body mass index; B: Impact of tumour regression grade on PFS. BMI: Body mass index; TRG: Tumour regression grade.