Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer

doi:10.4251/wjgo.v14.i2.511

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Feb 15, 2022 (publication date) through Nov 21, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2022; 14(2): 511-524
Published online Feb 15, 2022. doi: 10.4251/wjgo.v14.i2.511

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Figure 1 Kaplan-Meier estimates for overall survival in advanced esophageal cancer patients receiving or not receiving chemotherapy.

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Figure 2 Adjusted log relative hazard for chemotherapy compared with no chemotherapy over 10 mo from esophageal cancer diagnosis whereby the effect of chemotherapy on overall survival varies with time and is associated with improved overall survival up until 10 mo, after which there is no chemotherapy effect on overall survival. Dashed lines represent estimated 95% confidence intervals of the hazard ratios (HRs). The dotted horizontal line denotes no chemotherapy effect. The adjusted HR is estimated by a multivariable model including chemotherapy, age, gender, race, insurance type, treatment site, geographic location, number of comorbidities, grade, and American Joint Committee on Cancer T stage.

Citation: Midthun L, Kim S, Hendifar A, Osipov A, Klempner SJ, Chao J, Cho M, Guan M, Placencio-Hickok VR, Gangi A, Burch M, Lin DC, Waters K, Atkins K, Kamrava M, Gong J. Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer. World J Gastrointest Oncol 2022; 14(2): 511-524
URL: https://www.wjgnet.com/1948-5204/full/v14/i2/511.htm
DOI: https://dx.doi.org/10.4251/wjgo.v14.i2.511