Dysbiosis of the duodenal microbiota as a diagnostic marker for pancreaticobiliary cancer

Figure 1 Analysis of the duodenal microbiota. A, B: Bifidobacterium levels were significantly higher in the malignant group than in the benign group; A, C: Clostridium cluster XVIII levels were significantly higher in the malignant group than in the benign group; A, D: Prevotella levels were significantly higher in the benign group than in the malignant group. B: Benign group; M: Malignant group.

Figure 2 Comparison of the ability of microbiome components and cancer antigen 19-9 Levels to diagnose pancreaticobiliary cancer. The area under the receiver operating characteristic curve of Clostridium cluster XVIII was the highest among the three microbes and cancer antigen 19-9 Levels. CA19-9: Cancer antigen 19-9; AUC: The area under the curve.