Genetic variation of TGF-ΒR2 as a protective genotype for the development of colorectal cancer in men

Figure 1 Serum levels of transforming growth factor beta 1 in colorectal cancer patients compared to healthy controls above 50 years. Results are presented as median and interquartile range. ^aP < 0.001, *extremes, ◦outliers.

Figure 2 Transforming growth factor beta serum levels in colorectal cancer patients and healthy controls above 50 years. A: Depending on the TGF-ΒR2 -875G/A genotype; B: Depending on the female CRC patients and controls; C: Depending on the male CRC patients and controls. Results are presented as median and interquartile range. ^aP < 0.05, ^bP < 0.001, ◦outliers.

Figure 3 Transforming growth factor beta 1 serum levels in early and advanced colorectal cancer and healthy persons above 50 years-genotyped for the TGF-ΒR2 -875G/A. Results are presented as median and interquartile range. *Extremes, ◦outliers.

Figure 4 Transforming growth factor beta 1 serum levels in early and advanced colorectal cancer and healthy persons above 50 years. A: Regarding genotype; B: Regarding sex of the patients. Results are presented as median and interquartile range. ^aP < 0.05, ^bP < 0.001, *extremes, ◦outliers.