Prediction of malignancy and adverse outcome of solid pseudopapillary tumor of the pancreas

Figure 1 Publications concerning solid pseudopapillary tumor of the pancreas in PubMed, and number of pancreatectomies and patients undergoing surgery for solid pseudopapillary tumor of the pancreas in Huashan Hospital affiliated to Fudan University. Literature retrieved from PubMed (March 1, 2018) with the search terms “frantz tumor”, “solid and cystic papillary epithelial neoplasm”, “solid and cystic tumor”, “papillary cystic tumor”, “solid and papillary neoplasm”, “papillary cystic carcinoma”, “papillary and cystic tumor”, “papillary and solid neoplasm”, “solid and papillary epithelial neoplasm”, “papillary cystic neoplasm”, “solid pseudopapillary tumor”, “pancreas”, and “pancreatic” in “all fields”. SPTP: Solid pseudopapillary tumor of the pancreas.

Figure 2 Solid pseudopapillary tumor of the pancreas presenting with invasion into the portal splenic confluence. A: Enhanced computed tomography scan revealed intraluminal filling defect in the portal splenic confluence (arrow); B: An abnormal signal of the pancreatic head (arrow) and high signal foci in the right anterior lobe of the liver (yellow arrow) can be readily delineated from the coronal magnetic resonance imaging (MRI) section; C: Splenic vein tumor thrombus was noted by hematoxylin-eosin staining (× 100).

Figure 3 High uptake of F-18-fluorodeoxyglucose in a patient with solid pseudopapillary tumor of the pancreas. SPTP in a 25-year-old female patient with a T2 stage tumor. A: CT scan revealed a 5-cm isodense mass in the pancreatic head. B and C: Transaxial PET/CT (B) and PET (C) showed a hypermetabolic lesion with the maximum standardized uptake value of 33. She was disease free for 32 mo after surgical resection. SPTP: Solid pseudopapillary tumor of the pancreas; PET/CT: Position emission tomography/computed tomography.

Figure 4 Factors associated with malignant solid pseudopapillary tumor of the pancreas by univariate analysis.

Figure 5 Predictors for adverse outcome of solid pseudopapillary tumor of the pancreas after surgical resection by univariate analysis. WHO: World Health Organization; SPC: Solid pseudopapillary carcinoma; AJCC: American Joint Committee on Cancer; ENETS: European Neuroendocrine Tumour Society.