Telomere function in colorectal cancer

doi:10.4251/wjgo.v1.i1.3

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Oct 15, 2009 (publication date) through Nov 21, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2009; 1(1): 3-11
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.3

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Figure 1 Representative X-ray film for telomere length analysis by Southern blotting. Pt1-Pt4: Patients with colorectal carcinoma; T: Tumour tissues; N: Their paired normal samples; C: Positive control; M: DNA molecular weight marker; kb: Kilobase pairs.

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Figure 2 Telomerase activity in tissue extracts from two patients affected by colorectal cancer. In this representative experiment, telomerase activity was investigated in tumour (T) and non tumour (N) samples using the telomerase repeat amplification protocol (TRAP). As it is indicated in the figure, to avoid the effect of Taq DNA polymerase inhibitors, different extract dilutions were investigated.

Citation: Frías C, Morán A, de Juan C, Ortega P, Fernández-Marcelo T, Sánchez-Pernaute A, Torres AJ, Díaz-Rubio E, Benito M, Iniesta P. Telomere function in colorectal cancer. World J Gastrointest Oncol 2009; 1(1): 3-11
URL: https://www.wjgnet.com/1948-5204/full/v1/i1/3.htm
DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.3