Academic Content and Language Evaluation of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
- Total Article Views (13112)
All Articles published online
|
Publishing Process of This Article
|
Jan 15, 2017 (publication date) through Jul 18, 2025
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Oncology
ISSN
1948-5204
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Hayashi K, Anzai N. Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment. World J Gastrointest Oncol 2017; 9(1): 21-29 [PMID: 28144396 DOI: 10.4251/wjgo.v9.i1.21] |
|---|---|
| URL: | https://www.wjgnet.com/1948-5204/full/v9/i1/21.htm |
| Number | Citing Articles |
| 1 |
Sara Cano-Crespo, Josep Chillarón, Alexandra Junza, Gonzalo Fernández-Miranda, Judit García, Christine Polte, Laura R. de la Ballina, Zoya Ignatova, Óscar Yanes, Antonio Zorzano, Camille Stephan-Otto Attolini, Manuel Palacín. CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-50547-9
|
| 2 |
Mariafrancesca Scalise, Raffaella Scanga, Lara Console, Michele Galluccio, Lorena Pochini, Cesare Indiveri. Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark. Molecules 2021; 26(21): 6562 doi: 10.3390/molecules26216562
|
| 3 |
Hao Wu, Wen Su, Huimin Xu, Yang Zhang, Yunchao Li, Xiaohong Li, Louzhen Fan. Applications of carbon dots on tumour theranostics. VIEW 2021; 2(2) doi: 10.1002/VIW.20200061
|
| 4 |
Serena Dato, Eneida Hoxha, Paolina Crocco, Francesca Iannone, Giuseppe Passarino, Giuseppina Rose. Amino acids and amino acid sensing: implication for aging and diseases. Biogerontology 2019; 20(1): 17 doi: 10.1007/s10522-018-9770-8
|
| 5 |
Jingshun Zhang, Ying Xu, Dandan Li, Lulu Fu, Xueying Zhang, Yigang Bao, Lianwen Zheng. Review of the Correlation of LAT1 With Diseases: Mechanism and Treatment. Frontiers in Chemistry 2020; 8 doi: 10.3389/fchem.2020.564809
|
| 6 |
Philip F. Cohen, Tassia R. M. de Godoy, Kalevi Kairemo. Nuclear Medicine and Immunology. 2022; : 495 doi: 10.1007/978-3-030-81261-4_21
|
| 7 |
Johanna Huttunen, Santosh Kumar Adla, Magdalena Markowicz-Piasecka, Kristiina M. Huttunen. Increased/Targeted Brain (Pro)Drug Delivery via Utilization of Solute Carriers (SLCs). Pharmaceutics 2022; 14(6): 1234 doi: 10.3390/pharmaceutics14061234
|
| 8 |
Keitaro Hayashi, Osamu Kaminuma. Therapeutic Potential for Intractable Asthma by Targeting L-Type Amino Acid Transporter 1. Biomolecules 2022; 12(4): 553 doi: 10.3390/biom12040553
|
| 9 |
FEI CHU, KAI TONG, XIANG GU, MEI BAO, YANFEN CHEN, BIN WANG, YANHUA SHAO, LING WEI. Glutamine transporters as effective targets in digestive system malignant tumor treatment. Oncology Research 2024; 32(10): 1661 doi: 10.32604/or.2024.048287
|
| 10 |
Natesh Singh, Bruno O. Villoutreix, Gerhard F. Ecker. Rigorous sampling of docking poses unveils binding hypothesis for the halogenated ligands of L-type Amino acid Transporter 1 (LAT1). Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-51455-8
|
| 11 |
Ashok Singh Bahota, Keshav Kumar Singh, Arti Yadav, Rajni Chaudhary, Neelam Agrawal, Poonam Tandon. First principal study of interaction of copper doped gold nanoclusters with glycine. Inorganic Chemistry Communications 2023; 151: 110435 doi: 10.1016/j.inoche.2023.110435
|
| 12 |
Mariafrancesca Scalise, Lara Console, Filomena Rovella, Michele Galluccio, Lorena Pochini, Cesare Indiveri. Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring. Cells 2020; 9(9): 2028 doi: 10.3390/cells9092028
|
| 13 |
Stefan Bröer. Amino Acid Transporters as Disease Modifiers and Drug Targets. SLAS Discovery 2018; 23(4): 303 doi: 10.1177/2472555218755629
|
| 14 |
Hang Zhang, Xudong Zhao, Jin Wang, Wenyue Ji. Development and Validation of an Immune-Related Signature for the Prediction of Recurrence Risk of Patients With Laryngeal Cancer. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.683915
|
| 15 |
Shuhua Li, Wen Su, Hao Wu, Ting Yuan, Chang Yuan, Jun Liu, Gang Deng, Xingchun Gao, Zeming Chen, Youmei Bao, Fanglong Yuan, Shixin Zhou, Hongwei Tan, Yunchao Li, Xiaohong Li, Louzhen Fan, Jia Zhu, Ann T. Chen, Fuyao Liu, Yu Zhou, Miao Li, Xingchen Zhai, Jiangbing Zhou. Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids. Nature Biomedical Engineering 2020; 4(7): 704 doi: 10.1038/s41551-020-0540-y
|
| 16 |
Wirat Assawapanumat, Sopon Udomphon, Adun Kampaengtip, Sukanya Yaset, Xu Han, Pinunta Nittayacharn, Marvin T. Nieman, Chanisa Chotipanich, Witaya sungkarat, Panya Sunintaboon, Agata A. Exner, Norased Nasongkla. 99mTc /Spio-Loaded Polymeric Micelles as MRI and SPECT Imaging, Cancer-Targeted Nanoprobe for Liver Cancer Detection. SSRN Electronic Journal 2022; doi: 10.2139/ssrn.4115189
|
| 17 |
Huimin Xu, Jianqiao Chang, Hao Wu, Haoyu Wang, Wenjing Xie, Yunchao Li, Xiaohong Li, Yang Zhang, Louzhen Fan. Carbon Dots with Guanidinium and Amino Acid Functional Groups for Targeted Small Interfering RNA Delivery toward Tumor Gene Therapy. Small 2023; 19(31) doi: 10.1002/smll.202207204
|
| 18 |
Andrea Bonvini, Audrey Y Coqueiro, Julio Tirapegui, Philip C Calder, Marcelo M Rogero. Immunomodulatory role of branched-chain amino acids. Nutrition Reviews 2018; 76(11): 840 doi: 10.1093/nutrit/nuy037
|
| 19 |
Rashi Mathur, Ram Prakash Chauhan, Gurjaspreet Singh, Sweta Singh, Raunak Varshney, Ankur Kaul, Sanyog Jain, Anil Kumar Mishra. Tryptophan conjugated magnetic nanoparticles for targeting tumors overexpressing indoleamine 2,3 dioxygenase (IDO) and L-type amino acid transporter. Journal of Materials Science: Materials in Medicine 2020; 31(10) doi: 10.1007/s10856-020-06438-x
|
| 20 |
Kalishwaralal Kalimuthu, Bat-Chen Lubin, Andrii Bazylevich, Gary Gellerman, Ofer Shpilberg, Galia Luboshits, Michael A. Firer. Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells. Journal of Nanobiotechnology 2018; 16(1) doi: 10.1186/s12951-018-0362-1
|
| 21 |
Yu-Chuan Lin, Yi-Jang Lee, Yi-Wei Chen, Shan-Ying Wang, Fong-In Chou. Evaluation of the Key Advantages between Two Modalities of Boronophenylalanine Administration for Clinical Boron Neutron Capture Therapy Using an Animal Model. Cells 2022; 11(17): 2736 doi: 10.3390/cells11172736
|
| 22 |
Carina Stegmayr, Antje Willuweit, Philipp Lohmann, Karl-Josef Langen. O-(2-[18F]-Fluoroethyl)-L-Tyrosine (FET) in Neurooncology: A Review of Experimental Results. Current Radiopharmaceuticals 2019; 12(3): 201 doi: 10.2174/1874471012666190111111046
|
| 23 |
Takayoshi Owada, Kazuhiro Kurasawa, Hitoshi Endou, Tomoe Fujita, Naohiko Anzai, Keitaro Hayashi. LAT1-specific inhibitor ameliorates severe autoimmune arthritis in SKG mouse. International Immunopharmacology 2022; 109: 108817 doi: 10.1016/j.intimp.2022.108817
|
| 24 |
Minami Maekawa-Matsuura, Kei Fujieda, Yutaro Maekawa, Tomohiro Nishimura, Kenichi Nagase, Hideko Kanazawa. LAT1-Targeting Thermoresponsive Liposomes for Effective Cellular Uptake by Cancer Cells. ACS Omega 2019; 4(4): 6443 doi: 10.1021/acsomega.9b00216
|
| 25 |
Michael J Gerdes, Yesim Gökmen-Polar, Yunxia Sui, Alberto Santamaria Pang, Nicole LaPlante, Adrian L Harris, Puay-Hoon Tan, Fiona Ginty, Sunil S Badve. Single-cell heterogeneity in ductal carcinoma in situ of breast. Modern Pathology 2018; 31(3): 406 doi: 10.1038/modpathol.2017.143
|
| 26 |
Hai-Jun Liu, Peisheng Xu. Strategies to overcome/penetrate the BBB for systemic nanoparticle delivery to the brain/brain tumor. Advanced Drug Delivery Reviews 2022; 191: 114619 doi: 10.1016/j.addr.2022.114619
|
| 27 |
Satoshi Takeno, Yuki Yoshino, Teruhito Aihara, Masaaki Higashino, Yasukazu Kanai, Naonori Hu, Ryo Kakino, Ryo Kawata, Keiji Nihei, Koji Ono. Preliminary outcomes of boron neutron capture therapy for head and neck cancers as a treatment covered by public health insurance system in Japan: Real‐world experiences over a 2‐year period. Cancer Medicine 2024; 13(11) doi: 10.1002/cam4.7250
|
| 28 |
Meenakshi Dhanawat, Sumeet Gupta, Rina Das, Dinesh K. Mehta. LAT1: A POTENTIAL CEREBROVASCULAR TARGET TO BREACH BBB. Indian Drugs 2022; 59(03): 7 doi: 10.53879/id.59.03.12953
|
| 29 |
Woo Kyun Kim, Amit Kumar Singh, Jinquan Wang, Todd Applegate. Functional role of branched chain amino acids in poultry: a review. Poultry Science 2022; 101(5): 101715 doi: 10.1016/j.psj.2022.101715
|
| 30 |
Chen Song, Fanxuan Kong, Huijia Nong, Liu Cai, Ye Tian, Honghao Hou, Leyu Wang, Xiaozhong Qiu. Ammonium Persulfate-Loaded Carboxylic Gelatin–Methacrylate Nanoparticles Promote Cardiac Repair by Activating Epicardial Epithelial–Mesenchymal Transition via Autophagy and the mTOR Pathway. ACS Nano 2023; 17(20): 20246 doi: 10.1021/acsnano.3c06229
|
| 31 |
Keino Hutchinson, Dina Buitrago Silva, Joshua Bohlke, Chase Clausen, Allen A. Thomas, Massimiliano Bonomi, Avner Schlessinger. Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations. Biophysical Journal 2022; 121(23): 4476 doi: 10.1016/j.bpj.2022.11.001
|
| 32 |
Keitaro Hayashi, Naohiko Anzai. L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy. Journal of Pharmacological Sciences 2022; 148(1): 31 doi: 10.1016/j.jphs.2021.09.006
|
| 33 |
Elena Puris, Mikko Gynther, Seppo Auriola, Kristiina M. Huttunen. L-Type amino acid transporter 1 as a target for drug delivery. Pharmaceutical Research 2020; 37(5) doi: 10.1007/s11095-020-02826-8
|
| 34 |
Mariafrancesca Scalise, Lorena Pochini, Michele Galluccio, Lara Console, Cesare Indiveri. Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth. Frontiers in Oncology 2017; 7 doi: 10.3389/fonc.2017.00306
|
| 35 |
Danay Cibrian, Raquel Castillo-González, Nieves Fernández-Gallego, Hortensia de la Fuente, Inmaculada Jorge, María Laura Saiz, Carmen Punzón, Marta Ramírez-Huesca, Miguel Vicente-Manzanares, Manuel Fresno, Esteban Daudén, Javier Fraga-Fernandez, Jesús Vazquez, Julián Aragonés, Francisco Sánchez-Madrid. Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation. Journal of Allergy and Clinical Immunology 2020; 145(1): 199 doi: 10.1016/j.jaci.2019.09.025
|
| 36 |
Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, Nina Shibata, William E. Hume, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe. 18F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-52270-x
|
| 37 |
Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, Nina Shibata, William E. Hume, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe. Comparison of [18F]FIMP, [11C]MET, and [18F]FDG PET for early-phase assessment of radiotherapy response. Scientific Reports 2023; 13(1) doi: 10.1038/s41598-023-29166-y
|
| 38 |
Francisca Dias, Cristina Almeida, Ana Luísa Teixeira, Mariana Morais, Rui Medeiros. LAT1 and ASCT2 Related microRNAs as Potential New Therapeutic Agents against Colorectal Cancer Progression. Biomedicines 2021; 9(2): 195 doi: 10.3390/biomedicines9020195
|
| 39 |
Lili Quan, Ryuichi Ohgaki, Saori Hara, Suguru Okuda, Ling Wei, Hiroki Okanishi, Shushi Nagamori, Hitoshi Endou, Yoshikatsu Kanai. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation. Journal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01762-0
|
| 40 |
Zuzana Balážová, Igor Černý, Petr Vyškovský. Incidental Accumulation of Fluciclovine in Neuroendocrine Tumour in a Patient with Oncological Duplicity. Case Reports in Oncology 2020; 13(1): 431 doi: 10.1159/000506829
|
| 41 |
Fariba Shakeri, Parisa Mohamadynejad, Mehdi Moghanibashi. Identification of autophagy and angiogenesis modulators in colorectal cancer based on bioinformatics analysis. Nucleosides, Nucleotides & Nucleic Acids 2024; 43(4): 340 doi: 10.1080/15257770.2023.2259431
|
| 42 |
Ken Asada, Kazuma Kobayashi, Samuel Joutard, Masashi Tubaki, Satoshi Takahashi, Ken Takasawa, Masaaki Komatsu, Syuzo Kaneko, Jun Sese, Ryuji Hamamoto. Uncovering Prognosis-Related Genes and Pathways by Multi-Omics Analysis in Lung Cancer. Biomolecules 2020; 10(4): 524 doi: 10.3390/biom10040524
|
| 43 |
Grace S. Blount, Austin Seymour, Dylan Williams, Daylon Douglas, Joshua Miller, Sarah Sejoro, Karl E. Peace, Jannet Kocerha, Karelle S. Aiken. Structure–activity relationship investigations probing the cytotoxicity of 9‐aminoacridine derivatives with PC3 and A549. Journal of Heterocyclic Chemistry 2024; 61(9): 1439 doi: 10.1002/jhet.4869
|
| 44 |
Mariafrancesca Scalise, Michele Galluccio, Lara Console, Lorena Pochini, Cesare Indiveri. The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health. Frontiers in Chemistry 2018; 6 doi: 10.3389/fchem.2018.00243
|
| 45 |
Catarina Lopes, Carina Pereira, Rui Medeiros. ASCT2 and LAT1 Contribution to the Hallmarks of Cancer: From a Molecular Perspective to Clinical Translation. Cancers 2021; 13(2): 203 doi: 10.3390/cancers13020203
|
| 46 |
Janne Tampio, Susanne Löffler, Melina Guillon, Agathe Hugele, Johanna Huttunen, Kristiina M. Huttunen. Improved l-Type amino acid transporter 1 (LAT1)-mediated delivery of anti-inflammatory drugs into astrocytes and microglia with reduced prostaglandin production. International Journal of Pharmaceutics 2021; 601: 120565 doi: 10.1016/j.ijpharm.2021.120565
|
| 47 |
Daniel Morgan, Matthew Studham, Andreas Tjärnberg, Holger Weishaupt, Fredrik J. Swartling, Torbjörn E. M. Nordling, Erik L. L. Sonnhammer. Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-70941-y
|
| 48 |
Raffaella Scanga, Mariafrancesca Scalise, Fangrui Xiu, Michele Galluccio, Lara Console, Michele Visentin, Cesare Indiveri. Impact of 7-ketocholesterol on the function and stability of the LAT1 transporter. Biochemical Pharmacology 2025; 239: 117075 doi: 10.1016/j.bcp.2025.117075
|
| 49 |
Wirat Assawapanumat, Sopon Udomphon, Adun Kampaengtip, Sukanya Yaset, Xu Han, Pinunta Nittayacharn, Marvin T. Nieman, Chanisa Chotipanich, Witaya Sungkarat, Panya Sunintaboon, Agata A. Exner, Norased Nasongkla. 99mTc /SPIO-loaded polymeric micelles as MRI and SPECT imaging, cancer-targeted nanoprobe for liver cancer detection. Journal of Drug Delivery Science and Technology 2023; 79: 104060 doi: 10.1016/j.jddst.2022.104060
|
| 50 |
Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Kentaro Hisada, Sifan Feng, Yuichiro Kadonaga, Kazuhiro Ooe, Tadashi Watabe, Yoshiyuki Manabe, Atsushi Shimoyama, Masashi Murakami, Atsushi Toyoshima, Hiromitsu Haba, Yoshikatsu Kanai, Koichi Fukase. Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211. International Journal of Molecular Sciences 2024; 25(22): 12386 doi: 10.3390/ijms252212386
|
| 51 |
Hirofumi Hanaoka, Yasuhiro Ohshima, Aiko Yamaguchi, Hiroyuki Suzuki, Noriko S. Ishioka, Tetsuya Higuchi, Yasushi Arano, Yoshito Tsushima. Novel 18F-Labeled α-Methyl-Phenylalanine Derivative with High Tumor Accumulation and Ideal Pharmacokinetics for Tumor-Specific Imaging. Molecular Pharmaceutics 2019; 16(8): 3609 doi: 10.1021/acs.molpharmaceut.9b00446
|
| 52 |
Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, William Ewan Hume, Hisashi Doi, Yasuyoshi Watanabe. In vitro evaluation of (S)-2-amino-3-[3-(2-18F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid (18F-FIMP) as a positron emission tomography probe for imaging amino acid transporters. EJNMMI Research 2023; 13(1) doi: 10.1186/s13550-023-00988-1
|
| 53 |
Piman Pocasap, Natthida Weerapreeyakul, Juri Timonen, Juulia Järvinen, Jukka Leppänen, Jussi Kärkkäinen, Jarkko Rautio. Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7. International Journal of Molecular Sciences 2020; 21(6): 2132 doi: 10.3390/ijms21062132
|
| 54 |
Sasagu Kurozumi, Kyoichi Kaira, Hiroshi Matsumoto, Masafumi Kurosumi, Takehiko Yokobori, Yoshikatsu Kanai, Chikako Sekine, Chikako Honda, Ayaka Katayama, Mio Furuya, Sho Shiino, Takaya Makiguchi, Nigel P. Mongan, Emad A. Rakha, Tetsunari Oyama, Takaaki Fujii, Ken Shirabe, Jun Horiguchi. Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer. Scientific Reports 2022; 12(1) doi: 10.1038/s41598-022-06615-8
|
| 55 |
Gloria Pastor-Fernández, Isabel R. Mariblanca, María N. Navarro. Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities. Cells 2020; 9(9): 2044 doi: 10.3390/cells9092044
|
| 56 |
Go J. Yoshida. The Harmonious Interplay of Amino Acid and Monocarboxylate Transporters Induces the Robustness of Cancer Cells. Metabolites 2021; 11(1): 27 doi: 10.3390/metabo11010027
|
| 57 |
Kentaro Okunushi, Tomomi Furihata, Hanae Morio, Yasuhide Muto, Kosuke Higuchi, Meika Kaneko, Yusuke Otsuka, Yuta Ohno, Yasuhiro Watanabe, Yoshie Reien, Kiyoshi Nakagawa, Shinichi Sakamoto, Hidefumi Wakashin, Naoki Shimojo, Naohiko Anzai. JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function. Journal of Pharmacological Sciences 2020; 144(1): 16 doi: 10.1016/j.jphs.2020.06.006
|