Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome

Table 1 The densities of different endocrine cell types in controls, IBS-total, IBS-D, IBS-M and IBS-C

Endocrine cell type	Controls	IBS-total	IBS-D	IBS-M	IBS-C
Ghrelin	389 (320, 771)	359 (130, 966)	996 (529, 1154)a	358 (120, 966)	126 (0, 262)c
Serotonin	63 (51, 82)	51 (25, 115)	120 (69, 128)a	74 (47, 123)	40 (0, 46)b
Somatostatin	97 (72, 126)	72 (0, 206)	29 (0, 80)b	46 (0, 103)a	206 (194, 314)c

Values are expressed as median and interquartile (25^th and 75^th).

^aP < 0.05,

^bP < 0.01 and

^cP < 0.0001 vs controls. IBS: Irritable bowel syndrome; IBS-total: All patients with irritable bowel syndrome; IBS-D: Patients with diarrhea as the predominant syndrome; IBS-M: Patients with both diarrhea and constipation; IBS-C: Patients with constipation as the predominant syndrome.