Risk of colorectal polyps in patients with sporadic gastric polyps: A case-control study

Table 1 Characteristics of the patients (cases and controls)

Characteristics of patients	With gastric polyps (n = 78)	Without gastric polyps (n = 169)	P value
Age years old (average ± SD)	62 ± 11	61 ± 14	0.51
Sex (%women, CI)	71% (59-81)	61% (53-68)	0.11
Gastric polyps (%patients, CI)
Fundic gland polyps	80% (69-88)	Did not have gastric polyps
Hyperplastic	20% (12-31)
Indications of the UGIEs (%patients, CI)
Epigastralgia	38% (29-50)	46% (39-54)	0.14
Gastroesophageal reflux	22% (13-32)	9% (5-15)	< 0.01
Anemia	10% (4-19)	8% (4-13)	0.32
Abdominal pain	8% (3-16)	10% (6-16)	0.31
Digestive bleeding	4% (1-10)	6 % (3-11)	0.30
Screening	6 % (2-14)	9% (5-14)	0.35
Other	12% (4-19)	12% (4-13)	0.32
Gastric mucosa histology (%patients, CI)
Minor gastritis	76% (65-85)	68% (60-76)	0.15
Severe gastritis	24% (15-35)	32% (24-39)	0.15
Helicobacter pylori infection (%positives, CI)	20% (11-31)	29% (22-38)	0.07
Indications of the colonoscopies (%patients, CI)
Screening	37% (26-49)	43% (35-50)	0.25
Abdominal pain	17% (9-27)	23% (17-30)	0.16
Constipation	18% (10-28)	7% (3-11)	< 0.01
Anemia	13% (6-22)	9% (5-14)	0.23
Digestive bleeding	4% (1-11)	7% (3-12)	0.24
Other	11% (5-21)	11% (6-15)	0.12
Colonic polyps (%patients, CI)	25% (16-37)	20% (14-26)	0.17
Type of colonic polyps (%colonic polyps, CI)
Hyperplastic	25% (7-52)	31% (16-49)	0.95
Adenomas	68% (41-89)	63% (45-78)	0.63
ANL	45% (16-76) of the adenomas	41% (21-63) of the adenomas	0.82

UGIEs: Upper gastrointestinal endoscopies; ANL: Advanced neoplastic lesions.

Table 2 Risk of developing colorectal polyps, adenomas and advanced neoplastic lesions

	Colonic polyps	Colonic adenomas	ANL
	(OR, 95%CI)	(OR, 95%CI)	(OR, 95%CI)
Presence of gastric polyps	1.41	1.63	1.67
	(0.75-2.68)	(0.77-3.42)	(0.56-5.01)
Presence of gastric fundic gland polyps	1.56	1.78	0.8
	(0.80-3.04)	(0.82-3.84)	(0.21-2.98)

ANL: Advanced neoplastic lesions; OR: Odds ratio.

Table 3 Logistic regression

	P value
	Colonic polyps	Colonic adenomas	ANL
Female sex	0.488	0.121	0.369
GERD	0.457	0.969	0.525
Constipation	0.083	0.865	0.613
Helicobacter pylori infection	0.557	0.292	0.772

Influences of the analysed variables in the main outcomes. GERD: Gastroesophageal reflux disease; ANL: Advanced neoplastic lesions.