Efficacy of various endoscopic modalities in detecting dysplasia in ulcerative colitis: A systematic review and network meta-analysis

Table 1 The characteristics and outcomes of the included studies

Study	Ref.	Design	Reference	Comparator	Disease Type, Age	Reference			Comparator
						Bx with dysplasia/total bx (n)	Patients with dysplasia/total patients (n)	Bx with dysplasia/total patients (n)	Bx with Dysplasia/total Bx (n)	Patients with dysplasia/total patients (n)	Bx with dysplasia/total patients (n)
NBI HD vs WL HD	Dekker et al[32], 2007	PRCT	NBI HD	WL HD	UC, Adults	9/52	8/42	9/42	21/1550	7/42	21/42
	Van den Broek, et al[33], 2011	PRCT	NBI HD	WL HD	UC, Adults	13/105	8/48	13/48	14/1657	12/48	14/48
	Ignjatovic et al[34], 2012	PRCT	NBI HD	WL HD	UC, Adults	6/1380	5/56	6/56	7/1375	5/56	7/56
	Leifeld et al[35], 2015	PRCT	NBI HD	WL HD	UC, Adults	31/1883	22/159	31/159	30/7565	24/159	30/159
CE HD vs WL SD	Kiesslich et al[36], 2003	PRCT	CE HD	WL SD	UC, Adults	35/3545	13/84	35/84	10/3094	6/81	10/81
CE HD vs NBI HD	Watanabe et al[37], 2016	PRCT	CE HD	NBI HD	UC, Adults	19/181	11/130	19/130	27/183	17/133	27/133

UC: Ulcerative colitis; NBI: Narrow band imaging; CE: Chromoendoscopy; WL: White light; PRCT: Prospective randomized controlled trials; Bx: Biopsy.

Table 2 Jadad score and Cochrane Risk of Bias Assessment Instrument

Ref.	Was the study described as randomized?	Was the randomization scheme described and appropriate?	Was the study described as doubleblind?	Was the method of double blinding appropriate?	Was there a description of dropouts and withdrawals?	Total Jadad score	Se-quence generation (for arm randomization)	Allocation con-cealed	Blinding of outcomes	Incomplete outcome data addressed	ITT	Sample size calculation
Dekker et al[32], 2006	o	NA	o	o	o	4	x	x	o	o	o	o
Van den Broek et al[33], 2011	o	NA	x	NA	x	1	?	?	x	?	o	x
Ignjatovic et al[34], 2012	o	NA	o	NA	o	3	?	?	?	o	o	o
Leifeld et al[35], 2015	o	NA	x	NA	x	1	o	o	x	?	?	x
Kiesslich et al[36], 2003	o	o	o	NA	o	4	o	o	o	o	o	o
Watanabe et al[37], 2016	o	o	o	NA	o	4	o	o	o	o	o	o

ITT: Intention to treat; NA: Not available.