Systematic Reviews
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2020; 12(5): 159-171
Published online May 16, 2020. doi: 10.4253/wjge.v12.i5.159
Efficacy of various endoscopic modalities in detecting dysplasia in ulcerative colitis: A systematic review and network meta-analysis
Bilal Gondal, Haider Haider, Yuga Komaki, Fukiko Komaki, Dejan Micic, David T Rubin, Atsushi Sakuraba
Bilal Gondal, Haider Haider, Yuga Komaki, Fukiko Komaki, Dejan Micic, David T Rubin, Atsushi Sakuraba, Section of Gastroenterology, Hepatology and Nutrition, Department of Medicine, The University of Chicago Medicine, Chicago, IL 60637, United States
Bilal Gondal, Section of Gastroenterology, Carle Hospital, University of Illinois, Urbana, IL 61801, United States
Yuga Komaki, Fukiko Komaki, Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan
Author contributions: Gondal B, Komaki Y, Komaki F and Sakuraba A analyzed data; Gondal B drafted manuscript; Komaki Y and Komaki F and drafted figures; Haider H, Micic D and Rubin DT are responsible for critical review and approval of manuscript; Sakuraba A studied concept and design and wrote manuscript.
Conflict-of-interest statement: All authors testify that there are no disclosures or competing interests relevant to this publication.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Atsushi Sakuraba, MD, PhD, Assistant Professor, Department of Medicine, The University of Chicago Medicine, 5841 S, Maryland Ave, MC 4076, Chicago, IL 60637, United States. asakurab@medicine.bsd.uchicago.edu
Received: February 18, 2020
Peer-review started: February 18, 2020
First decision: March 28, 2020
Revised: April 12, 2020
Accepted: May 12, 2020
Article in press: May 12, 2020
Published online: May 16, 2020
Processing time: 87 Days and 10.4 Hours
Core Tip

Core tip: Ulcerative colitis (UC) is associated with increased neoplasia risk. Chromoendoscopy (CE), narrow band imaging (NBI) and random biopsy are used for surveillance, but data is limited to conclude best surveillance rank order. We did a network meta-analysis of UC surveillance randomized controlled trials. We identified 4 modalities; white light (WL) high definition (HD) or standard definition (SD), CE HD, and NBI HD. Results showed no differences among WL HD, NBI HD, and CE HD, while WLSD was inferior. The use of HD colonoscopes with or without image enhancement may provide improved detection of dysplasia in UC surveillance.