Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 10, 2016; 8(9): 385-390
Published online May 10, 2016. doi: 10.4253/wjge.v8.i9.385
Lower incidence of complications in endoscopic nasobiliary drainage for hilar cholangiocarcinoma
Kazumichi Kawakubo, Hiroshi Kawakami, Masaki Kuwatani, Shin Haba, Taiki Kudo, Yoko A Taya, Shuhei Kawahata, Yoshimasa Kubota, Kimitoshi Kubo, Kazunori Eto, Nobuyuki Ehira, Hiroaki Yamato, Manabu Onodera, Naoya Sakamoto
Kazumichi Kawakubo, Hiroshi Kawakami, Masaki Kuwatani, Shin Haba, Taiki Kudo, Yoko A Taya, Shuhei Kawahata, Yoshimasa Kubota, Kimitoshi Kubo, Kazunori Eto, Nobuyuki Ehira, Hiroaki Yamato, Manabu Onodera, Naoya Sakamoto, Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo 0608638, Japan
Author contributions: Kawakubo K designed and performed the study and wrote the paper; Kawakami H and Kuwatani M designed the study and supervised the writing of the report; Haba S, Kudo T, Taya YA, Kawahata S, Kubota Y, Kubo K, Eto K, Ehira N, Yamato H and Onodera M collected and analyzed the data; and Sakamoto N approved the final version of the manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Hokkaido University Hospital.
Informed consent statement: Patients were not required to give informed consent to participate in the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. For full disclosure, the details of the study are published on the home page of Hokkaido University Hospital.
Conflict-of-interest statement: The authors have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kazumichi Kawakubo, MD, PhD, Assistant Professor, Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Kita 15 Nishi 7, Kita-ku, Sapporo 0608638, Japan. kkawakubo-gi@umin.ac.jp
Telephone: +81-11-7161161 Fax: +81-11-7067867
Received: December 21, 2015
Peer-review started: December 22, 2015
First decision: January 30, 2016
Revised: February 15, 2016
Accepted: March 14, 2016
Article in press: March 16, 2016
Published online: May 10, 2016
Processing time: 136 Days and 20.1 Hours
Core Tip

Core tip: This retrospective study evaluated the risk of complications associated with a temporary endoscopic biliary drainage for hilar cholangiocarcinoma. Endoscopic nasobiliary drainage (ENBD) had a significantly lower incidence of biliary complications than biliary stenting. Endoscopic sphincterotomy significantly reduced the rate of post-endoscopic retrograde cholangiopancreatography pancreatitis, but was associated with bilateral drainage. Therefore, ENBD should be selected as a temporary biliary drainage method for patients with hilar cholangiocarcinoma.