Case Report
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 25, 2016; 8(4): 244-251
Published online Feb 25, 2016. doi: 10.4253/wjge.v8.i4.244
Gastric adenocarcinoma of fundic gland type: Endoscopic and clinicopathological features
Gen Tohda, Takeshi Osawa, Yasuyuki Asada, Masaki Dochin, Shintarou Terahata
Gen Tohda, Masaki Dochin, Department of Gastroenterology, Fukui Kosei Hospital, Fukui 918-8537, Japan
Takeshi Osawa, Yasuyuki Asada, Department of Surgery, Fukui Kosei Hospital, Fukui 918-8537, Japan
Shintarou Terahata, Department of Diagnostic Pathology, Tonami General Hospital, Tonami 939-1395, Japan
Author contributions: Tohda G wrote the manuscript; Osawa T and Asada Y contributed to the manuscript discussion; Dochin M and Terahata S reviewed the manuscript.
Institutional review board statement: This case report was reviewed and approved by the Fukui Kosei Hospital Institutional Review Board.
Informed consent statement: All involved persons gave their informed consent.
Conflict-of-interest statement: Authors have no conflict of interest relevant to this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Gen Tohda, MD, PhD, Department of Gastroenterology, Fukui Kosei Hospital, Shimo-rokujyo 201, Fukui 918-8537, Japan. genkipapa178@yahoo.co.jp
Telephone: +81-776-413377 Fax: +81-776-413372
Received: July 28, 2015
Peer-review started: August 6, 2015
First decision: September 23, 2015
Revised: December 20, 2015
Accepted: January 5, 2016
Article in press: January 7, 2016
Published online: February 25, 2016
Processing time: 208 Days and 17.5 Hours
Core Tip

Core tip: Gastric adenocarcinoma of fundic gland type (GA-FG) with chief cell differentiation is a new and extremely rare type of gastric adenocarcinoma, and the clinicopathological features of GA-FG have thus not yet been elucidated. In the present study, we discuss 4 cases of GA-FG that displayed low grade malignancy, slow-growth and less aggressive clinical behavior. Endoscopic submucosal dissection was performed and complete tumor resection was confirmed pathologically. None of the patients showed any signs of recurrence during the follow-up periods. We decided to report these rare cases because of their distinct endoscopic and clinicopathological features and unique biological behaviors.