Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Mar 16, 2015; 7(3): 192-205
Published online Mar 16, 2015. doi: 10.4253/wjge.v7.i3.192
Endoscopic treatment for gastrointestinal stromal tumor: Advantages and hurdles
Hyung Hun Kim
Hyung Hun Kim, Department of Internal Medicine, the Catholic University of Korea College of Medicine, Seoul 137-701, South Korea
Author contributions: Kim HH solely contributed to this paper.
Supported by The Science Research Program through the National Research Foundation of Korea (NRF); the Ministry of Science, ICT and Future Planning, No. NRF-2013R1A1A1009682.
Conflict-of-interest: There are no conflicts of interest regarding this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hyung Hun Kim, MD, Division of Gastroenterology, Department of Internal Medicine, the Catholic University of Korea College of Medicine, Seoul St. Mary’s Hospital, 222 Banpodaero, Seocho-Gu, Seoul 137-701, South Korea. drhhkim@gmail.com
Telephone: +82-2-22586065 Fax: +82-2-22582089
Received: July 15, 2014
Peer-review started: July 16, 2014
First decision: November 3, 2014
Revised: December 4, 2014
Accepted: December 18, 2014
Article in press: December 19, 2014
Published online: March 16, 2015
Processing time: 247 Days and 22.9 Hours
Core Tip

Core tip: Several endoscopic approaches have recently been investigated for removing gastrointestinal stromal tumors. Endoscopic enucleation has several advantages. However, there is the possibility of peritoneal seeding when accidental perforation occurs. Furthermore, the rate of R0 resection is not yet acceptable. While endoscopic full-thickness resection has a more solid theoretical basis than endoscopic enucleation in terms of R0 resection, the possibility of tumor cell shedding into the peritoneum would increase when capsule injury results from the procedure. Compared with endoscopy only procedures, laparoscopy endoscopy cooperative surgery and LAFTR provide a higher complete resection rate and a more stable process, which are accordant with the purpose of minimally destructive surgeries.