Retrospective Cohort Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 25, 2015; 7(17): 1243-1249
Published online Nov 25, 2015. doi: 10.4253/wjge.v7.i17.1243
Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia
Sophie SF Hon, Simon SM Ng, Tiffany CL Wong, Philip WY Chiu, Tony WC Mak, WW Leung, Janet FY Lee
Sophie SF Hon, Simon SM Ng, Tiffany CL Wong, Philip WY Chiu, Tony WC Mak, WW Leung, Janet FY Lee, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Author contributions: Hon SSF designed the study and drafted the manuscript; Ng SSM, Wong TCL and Chiu PWY designed study and data interpretation; Leung WW analysed data; Mak TWC and Lee JFY contributed to critical revision of the manuscript.
Informed consent statement: Consent from the participants was not obtained but the presented data are anonymized and risk of identification is low.
Conflict-of-interest statement: The authors have no conflicts of interest or financial conflicts to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Sophie SF Hon, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China. honsf@surgery.cuhk.edu.hk
Telephone: +852-26321495 Fax: +852-26377974
Received: April 30, 2015
Peer-review started: May 8, 2015
First decision: June 2, 2015
Revised: July 10, 2015
Accepted: September 30, 2015
Article in press: October 9, 2015
Published online: November 25, 2015
Core Tip

Core tip: This is the first study that compares endoscopic submucosal dissection (ESD) vs laparoscopic colorectal resection (LC) for endoscopically benign lesions that could not be adequately removed by conventional polypectomy. Case inclusion was based purely on the pre-operative/pre-procedure endoscopic findings. Although the difference in morbidities did not reach statistical significance, the absolute number of complications and the number of patients involved were much higher in the LC arm. The current study provided evidence that surgeons are capable of performing high-quality colorectal ESD procedures. We expect that the participation of the surgeons as well as the close collaboration with gastroenterologists will play a pivotal role in the formulation of a management plan for patients with early colorectal neoplasms.