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World J Gastrointest Endosc. Mar 16, 2014; 6(3): 68-73
Published online Mar 16, 2014. doi: 10.4253/wjge.v6.i3.68
Preoperative biliary drainage in hilar cholangiocarcinoma: When and how?
Woo Hyun Paik, Nerenthran Loganathan, Jin-Hyeok Hwang
Woo Hyun Paik, Nerenthran Loganathan, Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea
Jin-Hyeok Hwang, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi-do 463-707, South Korea
Author contributions: Paik WH reviewed the literature, and wrote and revised the manuscript; Loganathan N wrote and revised the manuscript; Hwang JH contributed to the conceptual design and critical revision of the manuscript.
Correspondence to: Jin-Hyeok Hwang, MD, PhD, Professor, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, South Korea. woltoong@snu.ac.kr
Telephone: +82-31-7877017 Fax: +82-31-7874051
Received: November 25, 2013
Revised: February 11, 2014
Accepted: March 3, 2014
Published online: March 16, 2014
Processing time: 108 Days and 10.4 Hours
Core Tip

Core tip: In selected patients, optimal preoperative management will improve the morbidity and mortality of hilar cholangiocarcinoma. Endoscopic nasobiliary drainage seems to be the most appropriate method of preoperative biliary drainage (PBD) in terms of minimizing the risk of tract seeding and inflammatory reactions. Percutaneous transhepatic biliary drainage could be a better option in certain cases such as advanced hilar cholangiocarcinoma or segmental cholangitis. Total biliary drainage is not usually recommended except in certain situations when the surgical technique is difficult without PBD or when patients develop cholangitis after unilateral drainage or a slow-resolving hyperbilirubinemia. Although the optimal preoperative bilirubin level is still a matter of debate, the shortest possible duration of PBD is recommended.