Meta-Analysis
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World J Gastrointest Endosc. Nov 16, 2014; 6(11): 549-554
Published online Nov 16, 2014. doi: 10.4253/wjge.v6.i11.549
Hyoscine for polyp detection during colonoscopy: A meta-analysis and systematic review
Imran Ashraf, Sohail Ashraf, Sameer Siddique, Douglas L Nguyen, Abhishek Choudhary, Matthew L Bechtold
Imran Ashraf, Sameer Siddique, Abhishek Choudhary, Matthew L Bechtold, Department of Medicine, University of Missouri, Columbia, MO 65212, United States
Sohail Ashraf, Department of Gastroenterology and Hepatology, Central Manchester University Hospitals, M139WL Manchester, United Kingdom
Douglas L Nguyen, Department of Medicine, University of California, Irvine, CA 92868, United States
Author contributions: Ashraf I, Choudhary A and Bechtold ML contributed equally to this work; Ashraf I, Ashraf S and Bechtold ML designed the research; Ashraf I, Ashraf S and Siddique S performed the research; Nguyen DL, Choudhary A and Bechtold ML analyzed the data; Ashraf I, Ashraf S and Siddique S wrote the paper; Nguyen DL, Choudhary A and Bechtold ML revised the manuscript.
Correspondence to: Matthew L Bechtold, MD, FASGE, FACG, Division of Gastroenterology and Hepatology, Department of Medicine, University of Missouri, Five Hospital Drive, Columbia, MO 65212, United States. bechtoldm@health.missouri.edu
Telephone: +1-573-8821013 Fax: +1-573-8844595
Received: May 6, 2014
Revised: September 10, 2014
Accepted: October 1, 2014
Published online: November 16, 2014
Processing time: 196 Days and 18.7 Hours
Core Tip

Core tip: Hyoscine is used in clinical practice to decrease spasms in the colon during colonoscopy in an effort to improve polyp or adenoma detection. However, this study shows that hyoscine given before the procedure or at time of cecal intubation does not improve polyp or adenoma detection.