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World J Gastrointest Endosc. May 16, 2013; 5(5): 231-239
Published online May 16, 2013. doi: 10.4253/wjge.v5.i5.231
Published online May 16, 2013. doi: 10.4253/wjge.v5.i5.231
Usefulness of applying lidocaine in esophagogastroduodenoscopy performed under sedation with propofol
Felipe de la Morena, Carlos Esteban, Beatriz de Cuenca, Endoscopy Unit, Department of Gastroenterology, Hospital Universitario Infanta Cristina, CP 28981 Parla, Madrid, Spain
Cecilio Santander, Ricardo Moreno, Department of Gastroenterology, Hospital Universitario de la Princesa, CP 28006 Madrid, Spain
Juan Antonio García, Department of Anaesthesiology, Hospital Universitario Infanta Cristina, CP 28981 Parla, Madrid, Spain
Javier Sánchez, Department of Pharmacology, Hospital Universitario Infanta Cristina, CP 28981 Parla, Madrid, Spain
Author contributions: de la Morena F performed all the esophagogastroduodenoscopies, designed the protocol, and wrote the manuscript; de Cuenca B, Santander C and Moreno R revised and approved the final manuscript for submission; Sánchez J provided pharmacological support, established and ensured blinding of the recruitment; García JA coordinated and administered the propofol sedation for all study participants; Esteban C participated in quality assessment of the statistical analyses.
Supported by Empresa Pública Hospital del Sur, Parla (Madrid) Spain
Correspondence to: Dr. Felipe de la Morena, Endoscopy Unit, Department of Gastroenterology, Hospital Universitario Infanta Cristina, Avenida 9 de Junio 2, CP 28981 Parla, Madrid, Spain. felipe_de_la_morena@hotmail.com
Telephone: +34-91-1913100 Fax: +34-91-1913950
Received: January 21, 2013
Revised: March 5, 2013
Accepted: April 10, 2013
Published online: May 16, 2013
Processing time: 113 Days and 13.4 Hours
Revised: March 5, 2013
Accepted: April 10, 2013
Published online: May 16, 2013
Processing time: 113 Days and 13.4 Hours
Core Tip
Core tip: We are pleased to report the second study in the literature about the possible efficacy of using an adjuvant topical anaesthesia, in this case lidocaine applied as a spray to the oropharynx, during esophagogastroduodenoscopy performed under sedation with propofol. This study is unique, however, in that it is the first randomized controlled trial demonstrating that this routine application has no beneficial effect on reduction of propofol dose or procedure-related complications, or on improved satisfaction of the endoscopist or anaesthetist. These findings may help to improve and streamline the current procedures used for endoscopy sedation, saving resources such as time during surgery and monetary costs for the topical agent.