Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2025; 17(4): 105238
Published online Apr 16, 2025. doi: 10.4253/wjge.v17.i4.105238
Clinical, endoscopic and histopathological observation of a rare case of esophageal submucosal gland duct adenoma: A case report
Ting Lu, Jun-Xing Liu, Yin Xia, Yan Zhao
Ting Lu, Yin Xia, Yan Zhao, Department of Pathology, Nanjing Medical University Affiliated Taizhou People’s Hospital, Jiangsu Taizhou People’s Hospital, Taizhou 225300, Jiangsu Province, China
Jun-Xing Liu, The Second Clinical Medical College, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China
Co-first authors: Ting Lu and Jun-Xing Liu.
Author contributions: Lu T and Liu JX contribute equally to this study as co-first authors; Lu T carried out experiments; Liu JX searched the literature and drafted manuscript; Xia Y aided in specimens collection; Zhao Y designed experiment methods, analyzed results, and revised manuscript; all authors had access and approved the last version of the manuscript.
Informed consent statement: The patient provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this paper.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Zhao, MD, PhD, Professor, Chief Physician, Department of Pathology, Nanjing Medical University Affiliated Taizhou People’s Hospital, Jiangsu Taizhou People’s Hospital, No. 366 Taihu Road, Taizhou 225300, Jiangsu Province, China. 15961057718@163.com
Received: January 16, 2025
Revised: March 10, 2025
Accepted: March 27, 2025
Published online: April 16, 2025
Processing time: 89 Days and 0.2 Hours
Core Tip

Core Tip: We present an exceedingly rare case of esophageal submucosal gland duct adenoma and conduct a comprehensive literature review to elucidate the origin, pathogenesis, clinical features, endoscopic and pathological characteristics, as well as potential genetic alterations of this tumor, thereby enhancing our understanding and preventing misdiagnosis.