Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Mar 16, 2025; 17(3): 98021
Published online Mar 16, 2025. doi: 10.4253/wjge.v17.i3.98021
Published online Mar 16, 2025. doi: 10.4253/wjge.v17.i3.98021
Efficacy and applications for PuraStat® use in the management of unselected gastrointestinal bleeding: A retrospective observational study
Raquel Ballester, Conor Costigan, Aoife Mary O'Sullivan, Shreyashee Sengupta, Deirdre McNamara, Department of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland
Raquel Ballester, Conor Costigan, Deirdre McNamara, Trinity Academic Gastroenterology Group, School of Medicine - Trinity College Dublin, Dublin D2, Ireland
Co-first authors: Raquel Ballester and Deirdre McNamara.
Author contributions: Ballester R and McNamara D designed the study; Ballester R, Costigan C, O’Sullivan AM, Sengupta S and McNamara D recruited data; Ballester R and McNamara D analyzed and interpreted data; Ballester R wrote the manuscript; McNamara D assessed and verified the study data; All authors critically reviewed and provided final approval of the manuscript, and all authors were responsible for the decision to submit the manuscript for publication.
Institutional review board statement: This study was approved by the Saint James’s Hospital and Tallaght University Hospital Joint Research and Ethics Committee (No. 2395), Dublin, Ireland.
Informed consent statement: The requirement for the acquisition of informed consent from patients was waived owing to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Raquel Ballester, MD, Department of Gastroenterology, Tallaght University Hospital, Belgard Road, Dublin D24, Ireland. ballestr@tcd.ie
Received: June 15, 2024
Revised: November 11, 2024
Accepted: February 8, 2025
Published online: March 16, 2025
Processing time: 271 Days and 18.3 Hours
Revised: November 11, 2024
Accepted: February 8, 2025
Published online: March 16, 2025
Processing time: 271 Days and 18.3 Hours
Core Tip
Core Tip: This study shows that PuraStat® is safe, effective and easy to use as hemostatic agent in multiple gastrointestinal bleeding sources, including lesions responsible for upper gastrointestinal bleeding. This is significant because many times, the standard of care treatment, such as sclerosant agents, hemoclips or soft coagulation forceps are not available or cannot be applied due to the lesions are placed in difficult positions, or there is underlying fibrosis of a diffuse bleeding.