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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Mar 16, 2025; 17(3): 102694
Published online Mar 16, 2025. doi: 10.4253/wjge.v17.i3.102694
Published online Mar 16, 2025. doi: 10.4253/wjge.v17.i3.102694
Long-term outcomes of endoscopic submucosal dissection for gastric dysplasia and early neoplasia in a United Kingdom Caucasian population
Sammi X Y Lim, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom
Elizabeth Ratcliffe, Ryan Wiltshire, James G S Whiteway, Stephen McGrath, Neeraj Prasad, Arash Assadsangabi, James Britton, Yeng S Ang, Department of Endoscopy and Gastroenterology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, United Kingdom
Javed Sultan, Department of Surgery, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, United Kingdom
Co-first authors: Sammi XY Lim and Elizabeth Ratcliffe.
Author contributions: Lim SXY and Ratcliffe E wrote the manuscript with input from all authors, they contributed equally to this article, they are the co-first authors of this manuscript; Ang YS supervised the project; Lim SXY, Wiltshire R, and Whiteway JGS collected and analyzed the data; Lim SXY, Ratcliffe E, Wiltshire R, Whiteway JGS, McGrath S, Sultan J, Prasad N, Assadsangabi A, Britton J, and Ang YS helped to shape the research, discussed the results and provided critical feedback and comments for the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Salford Royal Hospital Northern Care Alliance NHS Foundation Trust Institutional Review Board, confirm that the work done and presented in this manuscript is under “audit and service improvement” section of our directorate and as such no research ethical approval is required.
Informed consent statement: This letter is to confirm that the work done and presented in this manuscript is under “audit and service improvement” section of our directorate and as such no research ethical approval is required.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yeng S Ang, MD, Professor, Department of Endoscopy and Gastroenterology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford M6 8HD, United Kingdom. yeng.ang@nca.nhs.uk
Received: October 28, 2024
Revised: December 23, 2024
Accepted: February 12, 2025
Published online: March 16, 2025
Processing time: 139 Days and 14.2 Hours
Revised: December 23, 2024
Accepted: February 12, 2025
Published online: March 16, 2025
Processing time: 139 Days and 14.2 Hours
Core Tip
Core Tip: Through our ten-year retrospective analysis, there are clear improvements in the efficacy of gastric endoscopic submucosal dissection measured by en-bloc resection, endoscopic clearance, curative resection and local recurrence rates. Endoscopic submucosal dissection is demonstrated to be a safe and effective tool in treating gastric dysplasia and early neoplasia in the Caucasian population with acceptable rates of immediate and late complications, and survival duration.