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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2025; 17(2): 100665
Published online Feb 16, 2025. doi: 10.4253/wjge.v17.i2.100665
Published online Feb 16, 2025. doi: 10.4253/wjge.v17.i2.100665
Development and validation of a predictive model for endoscopic improvement of Crohn's disease
Hua-Gang Wang, Cang-La Nima, Qi Zhou, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Co-first authors: Hua-Gang Wang and Cang-La Nima.
Author contributions: Wang HG and Nima CL contributed equally to this study as co-first authors; Wang HG and Nima CL designed the study, collected and analyzed the data, and drafted the manuscript; Zhou Q designed and revised the manuscript.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (Approval No. TJ-IRB202409069).
Informed consent statement: This study only analyzed the data and was exempted from informed consent from the patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets used and analyzed in the current study are available from the corresponding author on reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qi Zhou, MD, PhD, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. m202276431@hust.edu.cn
Received: August 23, 2024
Revised: December 12, 2024
Accepted: January 11, 2025
Published online: February 16, 2025
Processing time: 174 Days and 16.1 Hours
Revised: December 12, 2024
Accepted: January 11, 2025
Published online: February 16, 2025
Processing time: 174 Days and 16.1 Hours
Core Tip
Core Tip: Endoscopic activity assessment is crucial for Crohn's disease (CD) patients. However, most current studies use serological indicators at the time of their visit to predict their current endoscopic activity, while doctors focus more on whether the patient's condition has improved compared to the previous visit. This study aimed to establish a clinical prediction model for evaluating the changes in endoscopic activity during follow-up visits. The final results indicate that the combined changes in albumin and fibrinogen between two visits can effectively predict whether the endoscopic activity of patients with CD will improve during follow-up visits.