Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jun 16, 2024; 16(6): 282-291
Published online Jun 16, 2024. doi: 10.4253/wjge.v16.i6.282
Organ and function preservation in gastrointestinal cancer: Current and future perspectives on endoscopic ablation
Youssef Yousry Soliman, Megan Soliman, Shravani Reddy, James Lin, Toufic Kachaamy
Youssef Yousry Soliman, Toufic Kachaamy, Department of Gastroenterology, City of Hope Phoenix, Goodyear, AZ 85338, United States
Megan Soliman, Department of Medicine, Medical Consulting, Goodyear, AZ 85395, United States
Shravani Reddy, Department of Gastroenterology, University of California Irvine, Irvine, CA 92697, United States
James Lin, Department of Gastroenterology, City of Hope National Medical Center, Duarte, CA 91010, United States
Author contributions: Soliman YY, Soliman M, and Kachaamy T created the outline and identified key areas to be addressed; Soliman YY and Soliman M drafted the initial manuscript; Reddy S authored the figures; Reddy S and Lin J contributed to critical review, edits, and improvement in grammatical content; Soliman YY was the corresponding author and incorporated edits and revisions.
Conflict-of-interest statement: Toufic Kachaamy has received fees for serving as a speaker, or consultant for Steris Endoscopy, Olympus, Pentax, Boston Scientific, Medtronic, and Microtech.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Youssef Yousry Soliman, MD, Assistant Professor, Department of Gastroenterology, City of Hope Phoenix, 14200 W Celebrate Life Way, Goodyear, AZ 85338, United States. soliman.joe@gmail.com
Received: February 1, 2024
Revised: March 13, 2024
Accepted: May 6, 2024
Published online: June 16, 2024
Processing time: 134 Days and 8.9 Hours
Core Tip

Core Tip: Endoscopic ablation of precancerous lesions is widely accepted in the luminal gastrointestinal tract. In unresectable gastrointestinal malignancy, the palliative role of endoscopic ablation is growing. Recently, the prospect of endoscopic ablation is expanding to include downstaging previously unresectable disease, as well as contributing to non-surgical complete clinical response as an adjunct therapy. The prospect for synergy in improving overall survival while balancing the quest for organ and function preservation warrants methodical investigations.