Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2024; 16(4): 193-205
Published online Apr 16, 2024. doi: 10.4253/wjge.v16.i4.193
Long-term outcomes after endoscopic removal of malignant colorectal polyps: Results from a 10-year cohort
Anna Fábián, Renáta Bor, Béla Vasas, Mónika Szűcs, Tibor Tóth, Zsófia Bősze, Kata Judit Szántó, Péter Bacsur, Anita Bálint, Bernadett Farkas, Klaudia Farkas, Ágnes Milassin, Mariann Rutka, Tamás Resál, Tamás Molnár, Zoltán Szepes
Anna Fábián, Renáta Bor, Tibor Tóth, Zsófia Bősze, Kata Judit Szántó, Péter Bacsur, Anita Bálint, Bernadett Farkas, Klaudia Farkas, Ágnes Milassin, Mariann Rutka, Tamás Resál, Tamás Molnár, Zoltán Szepes, Department of Internal Medicine, University of Szeged, Szent-Györgyi Albert Medical School, Szeged 6725, Hungary
Béla Vasas, Department of Pathology, University of Szeged, Szent-Györgyi Albert Medical School, Szeged 6725, Hungary
Mónika Szűcs, Department of Medical Physics and Medical Informatics, University of Szeged, Szent-Györgyi Albert Medical School, Szeged 6720, Hungary
Klaudia Farkas, USZ Translational Colorectal Research Group, Hungarian Centre of Excellence for Molecular Medicine, Szeged 6725, Hungary
Author contributions: Fábián A, Bor R, and Szepes Z designed the study; Tóth T, Bősze Zs, Szántó K, Bacsur P, Bálint A, Farkas B, Farkas K, Milassin Á, Rutka M, and Resál T collected and analyzed the data; Vasas B provided pathological revision of histological samples; Fábián A, and Szűcs M performed the statistical analysis; Fábián A drafted the manuscript; Bor R, Vasas B, Bősze Zs, Molnár T, and Szepes Z provided critical revision; All authors read and approved the final manuscript.
Supported by the New National Excellence Program of the Ministry for Innovation and Technology From the Source of the National Research, Development and Innovation Fund, No. ÚNKP-22-4-SZTE-296, No. ÚNKP-23-3-SZTE-268, and No. ÚNKP-23-5-SZTE-719; and the EU’s Horizon 2020 Research and Innovation Program under Grant Agreement, No. 739593.
Institutional review board statement: This study was carried out in accordance with the Helsinki Declaration and was approved by the Regional and Institutional Human Medical Biological Research Ethics Committee of University of Szeged (Clinical Trial Registration Number: 4137/2018).
Informed consent statement: As this was a retrospective cohort study, consent from patients was unnecessary.
Conflict-of-interest statement: All authors have no conflicts of interest to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Anna Fábián, MD, PhD, Assistant Lecturer, Attending Doctor, Department of Internal Medicine, University of Szeged, Szent-Györgyi Albert Medical School, Kálvária sgt. 57, Szeged 6725, Hungary. fabiananna9@gmail.com
Received: November 29, 2023
Peer-review started: November 29, 2023
First decision: December 27, 2023
Revised: January 28, 2024
Accepted: March 18, 2024
Article in press: March 18, 2024
Published online: April 16, 2024
Core Tip

Core Tip: Despite recent advancements in endoscopy and the ability to perform optical diagnoses, submucosal invasion in colorectal polyps is often diagnosed at post-polypectomy histological evaluations. The reporting of high-risk histological features cannot serve as the sole basis of optimal post-polypectomy management strategy. Long-term adverse outcomes after endoscopic resection of malignant colorectal polyps might be more common than previously reported, irrespective of whether secondary surgery was performed. Therefore, adherence to post-polypectomy surveillance colonoscopy should be improved.