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World J Gastrointest Endosc. Dec 16, 2024; 16(12): 647-660
Published online Dec 16, 2024. doi: 10.4253/wjge.v16.i12.647
Water-assisted colonoscopy in inflammatory bowel diseases: From technical implications to diagnostic and therapeutic potentials
Raffaele Pellegrino, Giovanna Palladino, Michele Izzo, Ilaria De Costanzo, Fabio Landa, Alessandro Federico, Antonietta Gerarda Gravina
Raffaele Pellegrino, Giovanna Palladino, Michele Izzo, Ilaria De Costanzo, Fabio Landa, Alessandro Federico, Antonietta Gerarda Gravina, Hepatogastroenterology Division, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples 80138, Italy
Author contributions: Pellegrino R, Palladino G, Izzo M, De Costanzo I, Landa F and Gravina AG collected the literature, and wrote the initial manuscript; Pellegrino R, Federico A and Gravina AG conceptualized the structure of the text, critically revised the manuscript for important intellectual content; Pellegrino R and Gravina AG conceptualized and drew the figures and table; All authors have read and approved the final manuscript.
Conflict-of-interest statement: Gravina AG has conducted training activities (e.g., ECM, preceptorship) for Pfizer, Galapagos Biopharma, and AbbVie. The remaining authors have no conflicts of interest to declare. The other authors have no direct or indirect conflicts of interest concerning this work to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Raffaele Pellegrino, MD, Hepatogastroenterology Division, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Via L de Crecchio, Naples 80138, Italy. raffaele.pellegrino@unicampania.it
Received: July 31, 2024
Revised: November 17, 2024
Accepted: November 26, 2024
Published online: December 16, 2024
Processing time: 133 Days and 13.3 Hours
Core Tip

Core Tip: Water-assisted colonoscopy (WAC) offers significant advantages over traditional gas-aided colonoscopy, particularly for patients with inflammatory bowel diseases (IBD). WAC enhances patient comfort, reduces procedural pain, and improves bowel cleanliness and mucosal visualisation. These improvements increased adenoma detection rates, enhanced diagnostic accuracy, and facilitated resective endoscopy. Given the elevated risk of colorectal cancer in IBD patients and, consequently, the increased frequency of endoscopic examinations in this population, WAC may prove beneficial for routine IBD endoscopies, ultimately improving the quality of care and patient outcomes.