Meta-Analysis
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2023; 15(9): 574-583
Published online Sep 16, 2023. doi: 10.4253/wjge.v15.i9.574
Comparison of trans-gastric vs trans-enteric (trans-duodenal or trans-jejunal) endoscopic ultrasound guided gallbladder drainage using lumen apposing metal stents
Dheera Grover, Ifrah Fatima, Murali Dharan
Dheera Grover, Department of Internal Medicine, University of Connecticut, Farmington, CT 06030, United States
Ifrah Fatima, Department of Internal Medicine, University of Missouri-Kansas City, Kansas City, MO 64110, United States
Murali Dharan, Department of Gastroenterology and Hepatology, University of Connecticut Health Center, Farmington, CT 06030, United States
Author contributions: Grover D and Fatima I contributed to literature search, literature inclusion for the study, and drafting of article; Dharan M contributed to conceptualization of research, literature search, critical revision of article and rewriting the discussions.
Conflict-of-interest statement: All co-authors of this manuscript confirm that there are no financial or personal relationships with any people or organizations that could inappropriately influence the actions of any author of this manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Murali Dharan, AGAF, FASGE, MRCP, Assistant Professor, Department of Gastroenterology and Hepatology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, United States. dharan@uchc.edu
Received: March 20, 2023
Peer-review started: March 20, 2023
First decision: June 19, 2023
Revised: July 25, 2023
Accepted: August 23, 2023
Article in press: August 23, 2023
Published online: September 16, 2023
Core Tip

Core Tip: Endoscopic ultrasound guided gallbladder drainage (EUS-GBD) is increasingly used in management of gallbladder disease. EUS-GBD can be achieved using trans-gastric or trans-enteric (trans-duodenal or trans-jejunal) approach There are currently no randomized controlled trials comparing these two approaches. We performed a meta-analysis of the existing literature on EUS guided gallbladder drainage. Trans-enteric approach was observed to have a more favorable safety profile compared to trans-gastric approach. Further use of cautery enhanced lumen apposing metallic stents (LAMS) to achieve EUS-guided GBD was associated with lesser adverse effects when compared to use of non-cautery enhanced (cold) LAMS.