Minireviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Mar 16, 2023; 15(3): 103-113
Published online Mar 16, 2023. doi: 10.4253/wjge.v15.i3.103
Endoscopic techniques for gastric neuroendocrine tumors: An update
Sara Massironi, Camilla Gallo, Alice Laffusa, Cristina Ciuffini, Clara Benedetta Conti, Federico Barbaro, Ivo Boskoski, Marco Emilio Dinelli, Pietro Invernizzi
Sara Massironi, Camilla Gallo, Pietro Invernizzi, Gastroenterology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza (MB) 20900, Italy
Alice Laffusa, Clara Benedetta Conti, Marco Emilio Dinelli, Interventional Endoscopy Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza (MB) 20900, Italy
Cristina Ciuffini, Federico Barbaro, Ivo Boskoski, Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore di Roma, Center for Endoscopic Research Therapeutics and Training (CERTT), Roma 00168, Italy
Author contributions: Massironi S conceptualization and review; Gallo C literature search, original draft writing, review, and editing; Laffusa A and Ciuffini C literature search and original draft writing; Conti CB and Barbaro F expert opinion and supervision; Boskoski I contributed to review; Dinelli ME and Invernizzi P contributed to supervision.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sara Massironi, MD, PhD, Chief Physician, Doctor, Medical Assistant, Research Scientist, Gastroenterology Unit, Fondazione IRCCS San Gerardo dei Tintori, 33 Via G.B. Pergolesi, Monza (MB) 20900, Italy. sara.massironi@libero.it
Received: September 25, 2022
Peer-review started: September 25, 2022
First decision: January 3, 2023
Revised: January 11, 2023
Accepted: February 8, 2023
Article in press: February 8, 2023
Published online: March 16, 2023
Processing time: 171 Days and 8.6 Hours
Core Tip

Core Tip: Gastric neuroendocrine neoplasms (gNENs) are a rare form of gastric neoplasia, although their incidence is increasing worldwide according to recent epidemiological reviews of large registries. The heterogeneity of gNENs poses a challenge, and therefore these neoplasms require different treatment strategies. Among the possible treatment options, the endoscopic approach is increasingly used and progressively improved, with different techniques available, ranging from classical polypectomy (cold or hot snare) to endoscopic mucosal resection (both with “en bloc” and piecemeal techniques), endoscopic submucosal dissection and endoscopic full-thickness resection. In this manuscript, we have summarized all new endoscopic techniques for the treatment of gastric neuroendocrine tumors.