Kerdsirichairat T, Shin EJ. Endoscopic ultrasound guided interventions in the management of pancreatic cancer. World J Gastrointest Endosc 2022; 14(4): 191-204 [PMID: 35634485 DOI: 10.4253/wjge.v14.i4.191]
Corresponding Author of This Article
Eun Ji Shin, MD, PhD, Associate Professor, Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, 1800 Orleans Street, Sheikh Zayed Tower/Suite 7125H, Baltimore, MD 21287, United States. eshin3@jhmi.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Apr 16, 2022; 14(4): 191-204 Published online Apr 16, 2022. doi: 10.4253/wjge.v14.i4.191
Endoscopic ultrasound guided interventions in the management of pancreatic cancer
Tossapol Kerdsirichairat, Eun Ji Shin
Tossapol Kerdsirichairat, Digestive Disease Center, Bumrungrad International Hospital, Bangkok 10120, Thailand
Eun Ji Shin, Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, United States
Author contributions: Both authors contributed equally to this work; Shin EJ approved the manuscript.
Conflict-of-interest statement: No conflict of interest related to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Eun Ji Shin, MD, PhD, Associate Professor, Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, 1800 Orleans Street, Sheikh Zayed Tower/Suite 7125H, Baltimore, MD 21287, United States. eshin3@jhmi.edu
Received: May 7, 2021 Peer-review started: May 7, 2021 First decision: July 27, 2021 Revised: August 9, 2021 Accepted: March 25, 2022 Article in press: March 25, 2022 Published online: April 16, 2022 Processing time: 336 Days and 6.3 Hours
Core Tip
Core Tip: Interventional endoscopic ultrasound in pancreatic cancer has been developed via a through-the-needle fashion, using 2 techniques: Injection and/or placement. Examples of through-the-needle injection techniques include intratumoral therapy, injection of alcohol and bupivacaine for celiac plexus neurolysis, and hydrogel for bleb formation to create space in the pancreaticoduodenal groove for dose-escalation stereotactic body radiation therapy. Examples of through-the-needle placement techniques include placement of fiducial markers, placement of ablative probes for non-thermal and thermal therapies, placement of radioactive seeds for brachytherapy, and placement of a lumen-apposing metal stent to create a gastrojejunostomy in patients with gastric outlet obstruction. The vast majority of these techniques have shown comparable or superior outcomes when compared to conventional interventions and therapies.
