Observational Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2021; 13(9): 407-415
Published online Sep 16, 2021. doi: 10.4253/wjge.v13.i9.407
Clinical characteristics and prognosis of patients with ulcerative colitis that shows rectal sparing at initial diagnosis
Yong-Sung Choi, Jong-Kyu Kim, Wan-Jung Kim
Yong-Sung Choi, Department of Internal Medicine, Daehang Hospital, Seoul 06699, South Korea
Jong-Kyu Kim, Wan-Jung Kim, Department of Gastroenterology, Daehang Hospital, Seoul 06699, South Korea
Author contributions: Choi YS designed the research study and wrote the manuscript; Kim JK and Kim WJ analyzed the data; all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Daehang Hospital on Feb 13, 2021 (Approval No. DH21-0001).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors disclosed no conflict of interest or financial relationships relevant to this publication.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at [yschoi427@naver.com]. Participants gave informed consent for data sharing.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Sung Choi, MD, Chief Doctor, Director, Staff Physician, Department of Internal Medicine, Daehang Hospital, 2151 Nambu Beltway, Seocho-Gu, Seoul 06699, South Korea. yschoi427@naver.com
Received: April 19, 2021
Peer-review started: April 19, 2021
First decision: June 13, 2021
Revised: June 23, 2021
Accepted: August 12, 2021
Article in press: August 12, 2021
Published online: September 16, 2021
Processing time: 143 Days and 22.3 Hours
Core Tip

Core Tip: Ulcerative colitis (UC) is characterised by mucosal inflammation from the rectum to its proximal area in a symmetric and continuous fashion. However, the atypical distribution of UC, such as skip inflammation or rectal sparing can be encountered at initial stage, making diagnosis difficult in usual practice although it is uncommon. As a matter of fact, some studies concerning pediatric UC patients were reported, but its clinical significance and incidence is not known well in adult UC patients. Our study is the only study that evaluated the clinical characteristics and prognosis of adult rectal sparing-typed UC compared with typical UC.