Pérez-Aguado G, de la Mata DMA, Valenciano CML, Sainz IFU. Endoscopic ultrasonography-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer: An update. World J Gastrointest Endosc 2021; 13(10): 460-472 [PMID: 34733407 DOI: 10.4253/wjge.v13.i10.460]
Corresponding Author of This Article
Guillermo Pérez-Aguado, MD, Associate Specialist, Department of Gastroenterology, Complejo Hospitalario Insular Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Avenida Marítima del Sur s/n, Las Palmas 35016, Spain. guiperez92@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Oct 16, 2021; 13(10): 460-472 Published online Oct 16, 2021. doi: 10.4253/wjge.v13.i10.460
Endoscopic ultrasonography-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer: An update
Guillermo Pérez-Aguado, Diego Martinez-Acitores de la Mata, Carlos Marra-López Valenciano, Ignacio Fernandez-Urien Sainz
Guillermo Pérez-Aguado, Department of Gastroenterology, Complejo Hospitalario Insular Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Las Palmas 35016, Spain
Diego Martinez-Acitores de la Mata, Ignacio Fernandez-Urien Sainz, Department of Gastroenterology, Endoscopy Unit, Complejo Hospitalario de Navarra CHN, Pamplona Navarra 31008, Spain
Carlos Marra-López Valenciano, Department of Gastroenterology, Endoscopy Unit, Agencia Sanitaria Costa del Sol, Málaga 29603, Spain
Author contributions: Guillermo Pérez Aguado: research of the bibliography; Aguado GP and de la Mata DMA edited and wrote the manuscript; Aguado GP and Sainz IFU edited the tables; de la Mata DMA edited the figures; Valenciano CML and Sainz IFU finally review the manuscript; All authors contributed to the research of the bibliography and proofreading and correction of grammar and structure.
Conflict-of-interest statement: No conflicts of interest are declared.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guillermo Pérez-Aguado, MD, Associate Specialist, Department of Gastroenterology, Complejo Hospitalario Insular Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Avenida Marítima del Sur s/n, Las Palmas 35016, Spain. guiperez92@gmail.com
Received: March 29, 2021 Peer-review started: March 29, 2021 First decision: June 17, 2021 Revised: June 27, 2021 Accepted: September 8, 2021 Article in press: September 8, 2021 Published online: October 16, 2021 Processing time: 198 Days and 12.4 Hours
Core Tip
Core Tip: In this review, we analyzed the efficacy of the celiac plexus neurolysis through echoendoscopy (EUS-CPN) technique in patients with unresectable pancreatic cancer. The use of opioids for pain control are associated with numerous side effects that reduce the quality of life of pancreatic cancer patients, and the use of EUS-CPN is a safe and effective approach to pain management and allows for the reduction in the opioid doses used. There are different techniques to perform a EUS-CPN, all of which are described in this article. However, there are concerns about the efficacy of EUS-CPN (since it produces a reduction in pain for a short time), the ideal time to perform this technique is unknown, and it is also unknown whether this technique has any influence on patient survival and quality of life.
