Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 16, 2020; 12(12): 555-559
Published online Dec 16, 2020. doi: 10.4253/wjge.v12.i12.555
Common bile duct lesions - how cholangioscopy helps rule out intraductal papillary neoplasms of the bile duct: A case report
Silvia Cocca, Giuseppe Grande, Luca Reggiani Bonetti, Paolo Magistri, Stefano Di Sandro, Fabrizio Di Benedetto, Rita Conigliaro, Helga Bertani
Silvia Cocca, Giuseppe Grande, Rita Conigliaro, Helga Bertani, Endoscopy Unit, Azienda Ospedaliero-Universitaria di Modena, Modena 41121, MO, Italy
Luca Reggiani Bonetti, Department of Pathologic Anatomy, University of Modena and Reggio Emilia, Modena 41124, MO, Italy
Paolo Magistri, Stefano Di Sandro, Fabrizio Di Benedetto, Hepato-pancreato-biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena 41124, MO, Italy
Author contributions: Bertani H, Grande G, Cocca S, Di Benedetto F and Di Sandro S treated the patient as endoscopists and surgeons, reviewed the literature and contributed to manuscript drafting; Magistri P reviewed the literature and contributed to manuscript drafting; Reggiani Bonetti L performed the histopathological analyses and interpretation and contributed to manuscript drafting; Conigliaro R, Di Benedetto F and Bertani H were responsible for revision of the manuscript for important intellectual content; all authors issued final approval of the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist, and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Silvia Cocca, MD, Doctor, Endoscopy Unit, Azienda Ospedaliero-Universitaria di Modena, Via del Pozzo, Modena 41121, MO, Italy. cocca.silvia@aou.mo.it
Received: August 18, 2020
Peer-review started: August 18, 2020
First decision: September 18, 2020
Revised: September 28, 2020
Accepted: November 4, 2020
Article in press: November 4, 2020
Published online: December 16, 2020
Core Tip

Core Tip: Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors, characterized by an exophytic growth exhibiting a papillary mass within the bile duct lumen and it can be localized anywhere along the biliary tree, with morphological variations and occasional invasion. We present a patient with obstructive jaundice who was diagnosed with IPNB using cholangioscopy during endoscopic retrograde cholangio-pancreatography. Using the SpyGlass DS II technology we were able to define tumor extension and to obtain targeted Spy-byte biopsies. The patient underwent successful surgical rsection of the tumor.