Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jan 16, 2020; 12(1): 17-22
Published online Jan 16, 2020. doi: 10.4253/wjge.v12.i1.17
Efficacy of mucosa-submucosa clip closure method after gastric endoscopic submucosal dissection
Satoshi Kinoshita, Toshihiro Nishizawa, Ai Fujimoto, Hideki Mori, Yoshihiro Nakazato, Masahiro Kikuchi, Toshio Uraoka
Satoshi Kinoshita, Toshihiro Nishizawa, Ai Fujimoto, Hideki Mori, Yoshihiro Nakazato, Masahiro Kikuchi, Department of Gastroenterology, National Hospital Organization Tokyo Medical Center, Tokyo 152-8902, Japan
Satoshi Kinoshita, Toshihiro Nishizawa, Ai Fujimoto, Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo 160-8582, Japan
Toshihiro Nishizawa, Department of Gastroenterology and Hepatology, International University of Health and Welfare Mita Hospital, Tokyo 108-8329, Japan
Toshio Uraoka, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Gunma University, Maebashi 371-8511, Japan
Author contributions: All authors helped to perform the research; Kinoshita S and Nishizawa T contributed to manuscript writing and data analysis; Kinoshita S, Nishizawa T, Fujimoto A and Mori H performed the procedures; Nakazato Y and Kikuchi M recruited the patients; Uraoka T developed the mucosa-submucosa clip closure method.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Tokyo Medical Center.
Informed consent statement: Informed consent was obtained from all patients.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Toshihiro Nishizawa, MD, PhD, Doctor, Department of Gastroenterology and Hepatology, International University of Health and Welfare Mita Hospital, Mita 1-4-3 Minato-ku, Tokyo 108-8329, Japan. nisizawa@kf7.so-net.jp
Received: May 15, 2019
Peer-review started: May 20, 2019
First decision: August 2, 2019
Revised: August 30, 2019
Accepted: November 6, 2019
Article in press: November 6, 2019
Published online: January 16, 2020
Processing time: 216 Days and 9.9 Hours
Core Tip

Core tip: The endoscopic mucosa-submucosa clip closure method is a simple closure method using only conventional clips. The success rate of the endoscopic mucosa-submucosa clip closure method was 68.2% (15/22) after gastric endoscopic submucosal dissection. The location and size of a mucosal defect were considered to be the main factors underlying difficulty in closure. Defects were relatively easy to close in the greater curvature of the upper or middle third stomach, because the gastric wall was relatively thin and soft and a front view approach could be taken.