Prospective Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2018; 10(11): 348-353
Published online Nov 16, 2018. doi: 10.4253/wjge.v10.i11.348
Submucosal injection of platelet-rich plasma in endoscopic resection of large sessile lesions
Vicente Lorenzo-Zúñiga, Vicente Moreno de Vega, Ramón Bartolí, Ingrid Marín, Noemí Caballero, Ignacio Bon, Jaume Boix
Vicente Lorenzo-Zúñiga, Vicente Moreno de Vega, Ramón Bartolí, Ingrid Marín, Noemí Caballero, Ignacio Bon, Jaume Boix, Department of Gastrointestinal Endoscopy, University Hospital Germans Trias/CIBERehd, Barcelona 08916, Spain
Author contributions: Lorenzo-Zúñiga V, Moreno de Vega V and Boix J contributed to the design of the study and performed the colonoscopies; Lorenzo-Zúñiga V and Bartolí R performed the data analysis and wrote the document; Marín I, Caballero N, and Bon I have revised the manuscript.
Institutional review board statement: The study was reviewed and approved by the institutional review board and Ethics Committee of University Hospital Germans Trias.
Informed consent statement: All study participants provided written consent prior to study enrolment.
Clinical trial registration: Study registered at ClinicalTrials.gov: NCT02931149.
Conflict-of-interest statement: The authors of this manuscript having no conflicts of interest to disclose.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Vicente Lorenzo-Zúñiga, MD, Professor, Department of Gastrointestinal Endoscopy, University Hospital Germans Trias, Carretera del Canyet s/n, Badalona 08916, Spain. vlorenzo.germanstrias@gencat.cat
Telephone: 00-34-934978866
Received: May 12, 2018
Peer-review started: May 12, 2018
First decision: July 9, 2018
Revised: August 8, 2018
Accepted: October 8, 2018
Article in press: October 10, 2018
Published online: November 16, 2018
Core Tip

Core tip: This was a prospective single-center study to evaluate the efficacy of submucosal injection of platelet-rich plasma (PRP) on 11 patients submitted to endoscopic resection of large lesions. PRP as lifting solution proved absence of delayed bleeding or perforation and strong healing activity.