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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Evaluation of the diagnostic and therapeutic utility of retrograde through-the-scope balloon enteroscopy and single-balloon enteroscopy
Yi Jia, Majd Michael, Mohammad Bashashati, Sherif Elhanafi, Christopher Dodoo, Alok K Dwivedi, Andres F Carrion, Mohamed O Othman, Marc J Zuckerman
Yi Jia, Majd Michael, Mohammad Bashashati, Sherif Elhanafi, Marc J Zuckerman, Division of Gastroenterology, Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, United States
Christopher Dodoo, Alok K Dwivedi, Biostatistics and Epidemiology Consulting Lab, Office of Research Resources and Division of Biostatistics and Epidemiology, Department of Molecular and Translational Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, United States
Andres F Carrion, Division of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, FL 33136, United States
Mohamed O Othman, Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77082, United States
Author contributions: Jia Y contributed to acquisition of data, analysis and interpretation of data, drafting the manuscript; Michael M, Bashashati M and Elhanafi S contributed to acquisition of data, analysis and interpretation of data and critical revision of the manuscript for important intellectual content; Dodoo C and Dwivedi AK contributed to statistical analysis; Carrion AF and Othman MO contributed to critical revision of the manuscript for important intellectual content; Zuckerman MJ contributed to study concept and design, acquisition of data, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, study supervision and guarantor; all authors reviewed and approved the final submitted manuscript.
Institutional review board statement: The study was approved by the Texas Tech University Health Sciences Center Institutional Review Board (Approval Number. E14078).
Conflict-of-interest statement: The authors have nothing to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at [marc.zuckerman@ttuhsc.edu]. Consent was not obtained but the presented data are anonymized and risk of identification is low.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Marc J Zuckerman, MD, Professor, Division of Gastroenterology, Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, 4800 Alberta Avenue, El Paso, TX 79912, United States. marc.zuckerman@ttuhsc.edu
Received: June 18, 2020
Peer-review started: June 18, 2020
First decision: September 11, 2020
Revised: September 26, 2020
Accepted: October 26, 2020
Article in press: October 26, 2020
Published online: November 16, 2020
Processing time: 150 Days and 13.9 Hours
ARTICLE HIGHLIGHTS
Research background
A new device has been introduced and designed to allow deep enteroscopy with a through-the-scope balloon which can be used for the more difficult retrograde approach.
Research motivation
To compare safety, feasibility and outcomes of retrograde enteroscopy performed by the novel through- the-scope enteroscopy (TTSE) and traditional single balloon enteroscopy (SBE) techniques.
Research objectives
To describe how retrograde enteroscopy with the novel TTSE differs from the traditional SBE and to provide an in-depth overview of both techniques with detailed description of clinical findings, success rate and outcomes.
Research methods
We performed a retrospective cohort study comparing clinical data and complications of retrograde TTSE and retrograde SBE in a community hospital. Technical success was considered as insertion of the enteroscope > 20 cm beyond the ileocecal valve.
Research results
Retrograde enteroscopy was safe and feasible using both systems. TTSE had comparable technical success, and reduced enteroscopy time compared with SBE, but with a lower capacity of small bowel insertion.
Research conclusions
TTSE is a promising method for retrograde examination of the small bowel in adults.
Research perspectives
Prospective multicenter studies to understand whether the findings of this study can be observed in other centers with different levels of experience and to compare the learning curve of TTSE vs SBE by different endoscopists.
