Luján-Sanchis M, Sanchis-Artero L, Larrey-Ruiz L, Peño-Muñoz L, Núñez-Martínez P, Castillo-López G, González-González L, Clemente CB, Albert Antequera C, Durá-Ayet A, Sempere-Garcia-Argüelles J. Current role of capsule endoscopy in Crohn’s disease. World J Gastrointest Endosc 2016; 8(17): 572-583 [PMID: 27668067 DOI: 10.4253/wjge.v8.i17.572]
Corresponding Author of This Article
Marisol Luján-Sanchis, MD, PhD, Digestive Diseases Unit, General University Hospital of Valencia, Avenida Tres Cruces, 2, 46014 Valencia, Spain. marisol.lujan@hotmail.es
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Sep 16, 2016; 8(17): 572-583 Published online Sep 16, 2016. doi: 10.4253/wjge.v8.i17.572
Current role of capsule endoscopy in Crohn’s disease
Marisol Luján-Sanchis, Laura Sanchis-Artero, Laura Larrey-Ruiz, Laura Peño-Muñoz, Paola Núñez-Martínez, Génesis Castillo-López, Lara González-González, Carlos Boix Clemente, Cecilia Albert Antequera, Ana Durá-Ayet, Javier Sempere-Garcia-Argüelles
Marisol Luján-Sanchis, Laura Sanchis-Artero, Laura Larrey-Ruiz, Laura Peño-Muñoz, Paola Núñez-Martínez, Génesis Castillo-López, Lara González-González, Carlos Boix Clemente, Cecilia Albert Antequera, Ana Durá-Ayet, Javier Sempere-Garcia-Argüelles, Digestive Diseases Unit, General University Hospital of Valencia, 46014 Valencia, Spain
Author contributions: Luján-Sanchis M designed the research, reviewed the literature and wrote the paper; Sanchis-Artero L made the tables, figures and illustrations; Larrey-Ruiz L ordered the references; Sempere-Garcia-Argüelles J performed critical final revision of manuscrip; rest of authors contributed equally to collecting the data.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest (including to commercial, personal, political, intellectual or religious interests). No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Marisol Luján-Sanchis, MD, PhD, Digestive Diseases Unit, General University Hospital of Valencia, Avenida Tres Cruces, 2, 46014 Valencia, Spain. marisol.lujan@hotmail.es
Telephone: +34-96-3131800 Fax: +34-96-1972148
Received: April 13, 2016 Peer-review started: April 16, 2016 First decision: May 19, 2016 Revised: May 25, 2016 Accepted: July 14, 2016 Article in press: July 18, 2016 Published online: September 16, 2016 Processing time: 152 Days and 13.1 Hours
Abstract
Capsule endoscopy (CE) currently plays an important role in Crohn’s disease (CD). It is a noninvasive technique that has led to a breakthrough in the endoscopic diagnosis of diseases of the small intestine. Its superior diagnostic performance and excellent safety profile lead to its considerable acceptance on the part of the patient. This paper reviews current indications of CE in three stages of clinical practice: Suspected CD, unclassified colitis and its extensive role in diagnosed CD. The diagnostic and therapeutic impact of the results of CE on the monitoring of this disease is also reviewed. Knowledge of its applications, the interpretation of its results in an appropriate context and the existence of a validated endoscopic activity index could change the way in which these patients are managed. The definition of mucosal healing and postoperative recurrence by means of endoscopic scoring systems will endow CE with new applications in the management of CD in the near future.
Core tip: We expose current indications and practical uses of capsule endoscopy in Crohn’s disease based on the most relevant published evidence. Likewise, we describe the diagnostic and therapeutic impact on this disease and an exhaustive summary of where it plays an extensive role.
