Clinical Trials Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2015; 7(5): 540-546
Published online May 16, 2015. doi: 10.4253/wjge.v7.i5.540
Tripartite comparison of single-incision and conventional laparoscopy in cholecystectomy: A multicenter trial
Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Qing-Bo Lai, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Zhi-Xiang Jian
Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China
Qing-Bo Lai, Zhi-Xiang Jian, Department of Hepatobiliary Surgery, Guangdong Provincial People’s Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China
Author contributions: Pan MX, Jian ZX designed research, contributed equally to this work; He GL, Jiang ZS, Cheng Y, Lai QB, Zhou CJ, Liu HY and Gao Y performed research; He GL, Zhou CJ and Cheng Y analyzed data; and He GL wrote the paper.
Supported by Hai Zhu district science and technology plans, GuangZhou, China, No. 2012-cg-26.
Ethics approval: The study was reviewed and approved by the Zhujiang Hospital Institutional Review Board.
Clinical trial registration: This study is registered at [http://www.zjyy.com.cn/]. The registration identification number is No.ZJYY-2013-GDEK-002.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: Ming-Xin Pan has received research funding from Hai Zhu district government, Guang Zhou, China; Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao and Ming-Xin Pan are employees of Zhujiang Hospital, Southern Medical University; Qing-Bo Lai and Zhi-Xiang Jian are employees of Guangdong Provincial People’s Hospital, Southern Medical University.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ming-Xin Pan, MD, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Number 253 Industry Road, Hai Zhu District, Guangzhou 510280, Guangdong Province, China. pmxyizjyy@126.com
Telephone: +86-20-62782560 Fax: +86-20-61643207
Received: December 15, 2014
Peer-review started: December 16, 2014
First decision: January 20, 2015
Revised: February 9, 2015
Accepted: April 1, 2015
Article in press: April 1, 2015
Published online: May 16, 2015
Processing time: 186 Days and 5.6 Hours
Abstract

AIM: To compare the characteristics of two single-incision methods, and conventional laparoscopy in cholecystectomy, and demonstrate the safety and feasibility.

METHODS: Three hundred patients with gallstones or gallbladder polyps were admitted to two clinical centers from January 2013 to January 2014 and were randomized into three groups of 100: single-incision three-device group, X-Cone group, and conventional group. The operative time, intraoperative blood loss, complications, postoperative pain, cosmetic score, length of hospitalization, and hospital costs were compared, with a follow-up duration of 1 mo.

RESULTS: A total of 142 males (47%) and 158 females (53%) were enrolled in this study. The population characteristics of these three groups is no significant differences exist in terms of age, sex, body mass index and American Society of Anesthesiology (P > 0.05). In results, there were no significant differences in blood loss, length of hospitalization, postoperative complications.The operative time in X-Cone group was significantly longer than other groups.There were significant differences in postoperative pain scores and cosmetic scores at diffent times after surgery (P < 0.05).

CONCLUSION: This study shows that this two single-incision methods are safe and feasible. Both methods are superior to the conventional procedure in cosmetic and pain scores.

Keywords: Cholecystectomy; Laparoscopic surgery; Single-incision laparoscopic cholecystectomy

Core tip: This is an article about single-incision laparoscopic surgery. It compares three methods in laparoscopic cholecystectomy. The study concludes that the three-device and X-Cone methods are safe and feasible for single-incision laparoscopic cholecystectomy. Compared with conventional laparoscopic cholecystectomy, single-incision laparoscopic surgery techniques have advantages in pain and cosmetic factors.