Minireviews
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 25, 2015; 7(19): 1311-1317
Published online Dec 25, 2015. doi: 10.4253/wjge.v7.i19.1311
Endoscopic options for treatment of dysplasia in Barrett’s esophagus
R Brooks Vance, Kerry B Dunbar
R Brooks Vance, Kerry B Dunbar, VA North Texas Healthcare System, Dallas VA Medical Center, University of Texas Southwestern Medical Center, Dallas, TX 75231, United States
Author contributions: Both Vance RB and Dunbar KB provided substantial contributions to conception and design, acquisition of data, as well as the drafting the article or revising it critically for important intellectual content, and gave final approval of the version to be published.
Conflict-of-interest statement: Dr. R Brooks Vance and Dr. Kerry B Dunbar have no conflicts of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kerry B Dunbar, MD, PhD, Associate Professor of Medicine, VA North Texas Healthcare System, Dallas VA Medical Center, University of Texas Southwestern Medical Center, 4500 South Lancaster Road, GI Lab CA 111-B1, Dallas, TX 75231, United States. kerry.dunbar@utsouthwestern.edu
Telephone: +1-214-8571603 Fax: +1-214-8571571
Received: April 28, 2015
Peer-review started: May 5, 2015
First decision: September 8, 2015
Revised: September 17, 2015
Accepted: November 10, 2015
Article in press: November 11, 2015
Published online: December 25, 2015
Processing time: 238 Days and 7.3 Hours
Abstract

Recent advances in the endoscopic treatment of dysplasia in Barrett’s esophagus (BE) have allowed endoscopists to provide effective and durable eradication therapies. This review summarizes the available endoscopic eradication techniques for dysplasia in patients with BE including endoscopic mucosal resection, endoscopic submucosal dissection, photodynamic therapy, argon plasma coagulation, radiofrequency ablation and cryotherapy.

Keywords: Dysplasia; Barrett’s esophagus; Endoscopic therapy; Endoscopic mucosal resection; Radiofrequency ablation; Endoscopy; Photodynamic therapy

Core tip: Endoscopic treatment of high-grade dysplasia in Barrett’s esophagus (BE) has become the standard of care for patients with this premalignant condition. In this review, we highlight the efficacy, durability and safety of the available endoscopic therapies for BE with high-grade dysplasia.