Munday WR, Kapur LH, Xu M, Zhang X. Russell body duodenitis with immunoglobulin kappa light chain restriction. World J Gastrointest Endosc 2015; 7(1): 73-76 [PMID: 25610537 DOI: 10.4253/wjge.v7.i1.73]
Corresponding Author of This Article
Xuchen Zhang, MD, PhD, Department of Pathology, VA CT HealthCare System and Yale University School of Medicine, 950 Campbell Ave, West Haven, CT 06516, United States. xuchen.zhang@yale.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Jan 16, 2015; 7(1): 73-76 Published online Jan 16, 2015. doi: 10.4253/wjge.v7.i1.73
Russell body duodenitis with immunoglobulin kappa light chain restriction
William R Munday, Lucy Harn Kapur, Mina Xu, Xuchen Zhang
William R Munday, Lucy Harn Kapur, Mina Xu, Xuchen Zhang, Department of Pathology, Yale University School of Medicine, New Haven, CT 06516, United States
Xuchen Zhang, Pathology and Laboratory Medicine Service, VA CT HealthCare System, West Haven, CT 06516, United States
Author contributions: Munday WR, Kapur LH and Zhang X contributed to the conception and design; Munday WR drafted and revised the manuscript; Zhang X and Xu M supervised and revised the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Xuchen Zhang, MD, PhD, Department of Pathology, VA CT HealthCare System and Yale University School of Medicine, 950 Campbell Ave, West Haven, CT 06516, United States. xuchen.zhang@yale.edu
Telephone: +1-203-9325711 Fax: +1-203-9374704
Received: August 11, 2014 Peer-review started: August 13, 2014 First decision: September 16, 2014 Revised: October 17, 2014 Accepted: October 31, 2014 Article in press: November 3, 2014 Published online: January 16, 2015 Processing time: 156 Days and 17.4 Hours
Abstract
Russell bodies are eosinophilic intracytoplasmic globules which are likely the result of disturbed secretion of immunoglobulins that accumulate within the plasma cell. Russell body collections have been identified within the stomach, known as Russell body gastritis. Similar lesions within the duodenum are referred to as Russell body duodenitis, which is rare. Several Russell body gastritis case reports are associated with Helicobacter pylori. However, the etiology of Russell body duodenitis remains unclear. Here we report the first case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.
Core tip: Russell body duodenitis is rare and the etiology is unclear. We report a case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.
